Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4014280 | 0.91 | EGLN1 (0.34) | CCR4MCL1P2RX7PTGDR2POLB | |
| SCHEMBL4008416 | 0.86 | CCR4 (0.39) | CCR4MCL1P2RX7KMOPTGDR2 | |
| SCHEMBL4012559 | 0.83 | CCR4 (0.40) | CCR4MCL1P2RX7KMOPTGDR2 | |
| SCHEMBL13769676 | 0.78 | MAPT (0.39) | P2RX7 | |
| SCHEMBL4007615 | 0.77 | SRC (0.43) | CCR4MCL1P2RX7POLB | |
| SCHEMBL4006629 | 0.76 | MAPT (0.38) | CCR4MCL1P2RX7POLBSMN1; SMN2 | |
| SCHEMBL4007097 | 0.76 | ALOX15 (0.36) | CCR4MCL1PTGDR2POLB | |
| SCHEMBL4008754 | 0.75 | FLT4 (0.44) | CCR4MCL1POLB | |
| SCHEMBL4006132 | 0.74 | P2RX7 (0.43) | P2RX7POLBRXRARXRBRXRG | |
| SCHEMBL4009501 | 0.74 | SCN9A (0.36) | CCR4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080682-A1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |