Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.60 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | YES1 | P07947 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4285483 | 0.95 | MEN1 (0.54) | KDM1AIDO1MEN1KMT2AALDH1A1 | |
| SCHEMBL4284310 | 0.94 | KDM1A (0.54) | KDM1AIDO1MEN1KMT2AALDH1A1 | |
| SCHEMBL4018480 | 0.82 | TPH1 (0.50) | KDM1AIDO1MEN1KMT2AALDH1A1 | |
| SCHEMBL4016883 | 0.81 | TPH1 (0.44) | KDM1AMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL5509419 | 0.78 | ADORA3 (0.44) | KDM1AIDO1MEN1KMT2AALDH1A1 | |
| SCHEMBL5687959 | 0.76 | ADORA2B (0.63) | MEN1KMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL4019166 | 0.75 | NOD1 (0.37) | KDM1AMEN1KMT2ABRDT | |
| SCHEMBL4016921 | 0.75 | ADORA2B (0.41) | HTTLMNA | |
| SCHEMBL4016181 | 0.74 | MEN1 (0.42) | KDM1AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL2327640 | 0.72 | ADORA2B (0.62) | KDM1AMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009157938-A1 | A2B ADENOSINE RECEPTOR ANTAGONISTS FOR TREATING CANCER | CV THERAPEUTICS, INC. (US) | 2009-12-30 | — | — | WO | disclosed |