Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D known ✓ | Q08499 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27495132 | 0.84 | MEN1 (0.54) | KMT2ATSHRLMNATDP1MEN1 | |
| SCHEMBL3772670 | 0.83 | MEN1 (0.57) | KMT2ATSHRLMNATDP1MEN1 | |
| SCHEMBL10497757 | 0.82 | POLB (0.70) | KMT2APOLBTSHRMAPK1LMNA | |
| Tetrabuthylammonium SCHEMBL4020213 | 0.82 | LMNA (0.44) | KMT2APOLBTSHRMAPK1LMNA | |
| SCHEMBL305422 | 0.82 | LMNA (0.56) | KMT2APOLBLMNATDP1PTPN1 | |
| SCHEMBL4017803 | 0.81 | SNCA (0.50) | KMT2APOLBTSHRMAPK1MEN1 | |
| SCHEMBL2328500 | 0.81 | POLB (0.48) | KMT2APOLBTSHRMAPK1LMNA | |
| SCHEMBL4016326 | 0.80 | SNCA (0.49) | KMT2APOLBTSHRMAPK1LMNA | |
| SCHEMBL11333846 | 0.80 | CA12 (0.46) | KMT2APOLBTSHRLMNATDP1 | |
| SCHEMBL29576203 | 0.80 | LMNA (0.54) | KMT2APOLBLMNATDP1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1085540-B1 | SOLID ELECTROLYTIC CAPACITOR AND METHOD FOR PREPARING THE SAME | SHOWA DENKO KK (JP) | 2009-07-01 | — | — | EP | disclosed |
| US-6466421-B1 | Solid electrolytic capacitor and method for producing the same | SHOWA DENKO K.K. (JP) | 2002-10-15 | — | — | US | disclosed |
| US-6344966-B1 | ELECTRICALLY CONDUCTING POLYMER LAYER CONTAINS AS A DOPANT AN ANION OF(1) ALKOXY-SUBSTITUTED NAPHTHALENESULFONATE, (2) A HETEROCYCLIC SULFONATE, OR (3) AN ANION OF AN ALIPHATIC POLYCYCLIC COMPOUND | SHOWA DENKO K.K. (JP) | 2002-02-05 | — | — | US | disclosed |
| EP-1085540-A1 | SOLID ELECTROLYTIC CAPACITOR AND METHOD FOR PREPARING THE SAME | Showa Denko K K (JP) | 2001-03-21 | — | — | EP | disclosed |
| US-5489583-A | FOR TREATING OR PREVENTING THROMBOSIS | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-06 | — | — | US | disclosed |
| US-4117127-A | INHIBITION AND SUPPRESSION OF THROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1978-09-26 | — | — | US | disclosed |
| US-4101653-A | ANTITHROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1978-07-18 | — | — | US | disclosed |
| US-4097591-A | ANTITHROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1978-06-27 | — | — | US | disclosed |
| US-4097472-A | INHIBITION AND SUPRESSION OF THROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1978-06-27 | — | — | US | disclosed |
| US-4093712-A | ANTITHROMBOGENIC AGENTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1978-06-06 | — | — | US | disclosed |
| US-4073892-A | ANTITHROMBOGENIC | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1978-02-14 | — | — | US | disclosed |
| US-4073913-A | INHIBITION AND SUPPRESSION OF THROMBIN | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1978-02-14 | — | — | US | disclosed |
| US-4071621-A | N2 -alkoxynaphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1978-01-31 | — | — | US | disclosed |
| US-4069318-A | INHIBITION AND SUPPRESSION OF THROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1978-01-17 | — | — | US | disclosed |
| US-4066773-A | ANTITHROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1978-01-03 | — | — | US | disclosed |