Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2870934 | 0.83 | PSIP1 (0.54) | PSIP1HSD11B1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL18257723 | 0.82 | ALDH1A1 (0.64) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL777601 | 0.79 | PSIP1 (0.67) | PSIP1HSD11B1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL19514690 | 0.79 | PSIP1 (0.50) | PSIP1HSD11B1MAPTALDH1A1L3MBTL1 | |
| Hydrogen Sulfide SCHEMBL6696519 | 0.79 | PSIP1 (0.55) | PSIP1HSD11B1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL730444 | 0.78 | PSIP1 (0.60) | PSIP1HSD11B1MAPTALDH1A1POLB | |
| SCHEMBL7829202 | 0.77 | HSD11B1 (0.50) | PSIP1HSD11B1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL680611 | 0.76 | PSIP1 (0.70) | PSIP1HSD11B1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL576918 | 0.75 | KEAP1 (0.63) | PSIP1HSD11B1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL10629823 | 0.75 | PSIP1 (0.61) | PSIP1HSD11B1MAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321270-B1 | IMPROVED PROCESS FOR THE ADDITION OF THIOLATES TO ALFA, BETA-UNSATURATED CARBONYL OR SULFONYL COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2016-03-23 | — | — | EP | disclosed |
| EP-2321270-B1 | IMPROVED PROCESS FOR THE ADDITION OF THIOLATES TO ALFA, BETA-UNSATURATED CARBONYL OR SULFONYL COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2016-03-23 | — | — | EP | disclosed |
| US-8101803-B2 | Process for the addition of thiolates to α,β-unsaturated carbonyl or sulfonyl compounds | DOW AGROSCIENCES LLC (US) | 2012-01-24 | — | — | US | disclosed |
| EP-2321270-A1 | IMPROVED PROCESS FOR THE ADDITION OF THIOLATES TO ALFA, BETA-UNSATURATED CARBONYL OR SULFONYL COMPOUNDS | Dow AgroSciences LLC (US) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010021855-A1 | IMPROVED PROCESS FOR THE ADDITION OF THIOLATES TO ALFA, BETA-UNSATURATED CARBONYL OR SULFONYL COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2010-02-25 | — | — | WO | disclosed |
| US-20100048939-A1 | PROCESS FOR THE ADDITION OF THIOLATES TO ?,?-UNSATURATED CARBONYL OR SULFONYL COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048939-A1 | PROCESS FOR THE ADDITION OF THIOLATES TO ?,?-UNSATURATED CARBONYL OR SULFONYL COMPOUNDS | CBS, TST, KCNJ1 | PSIP1 2525/4885HSD11B1 543/4885MAPT 2718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.