Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4033608 | 0.87 | ALOX15 (0.41) | ALDH1A1HPGDMAPTHTTKMT2A | |
| SCHEMBL4035745 | 0.81 | MMP1 (0.40) | ALDH1A1CHRM1 | |
| SCHEMBL4037876 | 0.81 | ALDH1A1 (0.46) | ALDH1A1CHRM1HPGDHTTKMT2A | |
| SCHEMBL6209492 | 0.79 | ALOX15 (0.41) | ALDH1A1HPGDMAPTHTTKMT2A | |
| SCHEMBL4034716 | 0.79 | P2RX7 (0.42) | — | |
| SCHEMBL4033601 | 0.76 | TP53 (0.40) | ALDH1A1LMNAMAPTHTTKMT2A | |
| SCHEMBL7090151 | 0.74 | EPHX2 (0.41) | RAB9AALDH1A1NR2F2NPC1MAPT | |
| SCHEMBL1386085 | 0.68 | MAPK1 (0.51) | ALDH1A1ATMLMNAHPGDMAPT | |
| SCHEMBL1381941 | 0.68 | PKM (0.54) | ALDH1A1ATMHPGDMAPTKMT2A | |
| SCHEMBL4034713 | 0.67 | ALDH1A1 (0.44) | ALDH1A1ATMLMNAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |