Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035745 | 0.91 | MMP1 (0.40) | ALDH1A1USP2KDM4EMMP1MMP3 | |
| SCHEMBL4034716 | 0.88 | P2RX7 (0.42) | — | |
| SCHEMBL1381941 | 0.87 | PKM (0.54) | ALDH1A1USP2PKMSMN1; SMN2KMT2A | |
| SCHEMBL4033612 | 0.81 | RAB9A (0.38) | ALDH1A1KMT2AHTTCHRM1HPGD | |
| SCHEMBL6209732 | 0.79 | ALDH1A1 (0.45) | ALDH1A1PKMKMT2AGAAHPGD | |
| SCHEMBL1386085 | 0.78 | MAPK1 (0.51) | ALDH1A1PKMSMN1; SMN2KMT2AGAA | |
| SCHEMBL4038385 | 0.78 | ALDH1A1 (0.57) | ALDH1A1USP2KDM4EPKMSMN1; SMN2 | |
| SCHEMBL4036566 | 0.77 | ALDH1A1 (0.62) | ALDH1A1USP2KDM4EPKMSMN1; SMN2 | |
| SCHEMBL4034713 | 0.76 | ALDH1A1 (0.44) | ALDH1A1PKMSMN1; SMN2HPGDMAPK1 | |
| SCHEMBL7090151 | 0.72 | EPHX2 (0.41) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |