Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.40 |
| ▸ | MMP3 | P08254 | 3/20 | 0.40 |
| ▸ | MMP7 | P09237 | 3/20 | 0.40 |
| ▸ | MMP9 | P14780 | 3/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4037876 | 0.91 | ALDH1A1 (0.46) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL4034716 | 0.89 | P2RX7 (0.42) | — | |
| SCHEMBL1386085 | 0.87 | MAPK1 (0.51) | GAAALDH1A1MAPK1 | |
| SCHEMBL4033612 | 0.81 | RAB9A (0.38) | ALDH1A1CHRM1 | |
| SCHEMBL4038551 | 0.79 | MMP1 (0.45) | MMP1MMP3MMP7MMP9FKBP1A | |
| SCHEMBL1381941 | 0.78 | PKM (0.54) | GAAALDH1A1USP2MAPK1 | |
| SCHEMBL4034713 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPK1 | |
| SCHEMBL4035389 | 0.76 | MMP1 (0.55) | MMP1MMP3MMP7MMP9FKBP1A | |
| SCHEMBL7090151 | 0.73 | EPHX2 (0.41) | KDM4EALDH1A1 | |
| SCHEMBL4033852 | 0.72 | TSHR (0.46) | MMP1MMP3MMP7MMP9FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |