Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 8/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 7/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.39 |
| ▸ | MMP9 | P14780 | 4/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP7 | P09237 | 2/20 | 0.35 |
| ▸ | MMP12 | P39900 | 2/20 | 0.35 |
| ▸ | MMP14 | P50281 | 2/20 | 0.35 |
| ▸ | MMP15 | P51511 | 2/20 | 0.35 |
| ▸ | MMP16 | P51512 | 2/20 | 0.35 |
| ▸ | MMP26 | Q9NRE1 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4033743 | 0.86 | RAB9A (0.45) | MMP1MMP13MMP9MMP3KDM4E | |
| SCHEMBL4035190 | 0.82 | ADAMTS4 (0.42) | MMP1ADAM17MMP13MMP9MMP3 | |
| SCHEMBL14499810 | 0.71 | MMP1 (0.48) | MMP1ADAM17MMP13MMP9MMP3 | |
| SCHEMBL14499807 | 0.71 | MMP1 (0.48) | MMP1ADAM17MMP13MMP9MMP3 | |
| SCHEMBL14499808 | 0.71 | MMP1 (0.48) | MMP1ADAM17MMP13MMP9MMP3 | |
| SCHEMBL14499809 | 0.71 | MMP1 (0.48) | MMP1ADAM17MMP13MMP9MMP3 | |
| SCHEMBL4038496 | 0.69 | PSEN1 (0.39) | MMP1MMP13MMP9MMP3KMT2A | |
| SCHEMBL4035688 | 0.69 | CA12 (0.39) | MMP9MMP2 | |
| SCHEMBL4038524 | 0.67 | MMP2 (0.34) | MMP1MMP9MMP3MMP2MMP12 | |
| SCHEMBL4033428 | 0.63 | MMP1 (0.59) | MMP1ADAM17MMP13MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |