Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4038524 | 0.77 | MMP2 (0.34) | CA12MMP9MMP2CA9 | |
| SCHEMBL4035190 | 0.72 | ADAMTS4 (0.42) | MMP9 | |
| SCHEMBL4033743 | 0.71 | RAB9A (0.45) | CA12CA2MMP9CA1CA9 | |
| SCHEMBL4035748 | 0.69 | MMP1 (0.40) | MMP9MMP2 | |
| SCHEMBL4032668 | 0.66 | THRB (0.36) | CA12CA2PTGDRTHRBCA1 | |
| SCHEMBL4037368 | 0.66 | CCR1 (0.39) | OPRK1 | |
| SCHEMBL4035430 | 0.65 | MMP1 (0.47) | MMP9 | |
| SCHEMBL1470570 | 0.63 | NOTUM (0.42) | PTGDRTHRB | |
| SCHEMBL1662635 | 0.62 | HDAC3 (0.49) | MMP9MMP2 | |
| SCHEMBL5800067 | 0.61 | PTGDR (0.53) | PTGDRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |