Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.34 |
| ▸ | MMP9 | P14780 | 3/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4037792 | 0.83 | ALDH1A1 (0.37) | MMP9MMP1MMP3 | |
| SCHEMBL4035688 | 0.77 | CA12 (0.39) | MMP2MMP9CA12CA9 | |
| SCHEMBL4033157 | 0.71 | DRD2 (0.37) | — | |
| SCHEMBL4217064 | 0.70 | FABP1 (0.42) | — | |
| SCHEMBL4208499 | 0.69 | GAA (0.47) | — | |
| SCHEMBL4035190 | 0.69 | ADAMTS4 (0.42) | MMP9MMP1MMP3 | |
| SCHEMBL4214876 | 0.68 | FABP1 (0.40) | — | |
| SCHEMBL4033743 | 0.68 | RAB9A (0.45) | MMP9MMP1MMP3CA12CA9 | |
| SCHEMBL4212852 | 0.67 | FABP1 (0.45) | — | |
| SCHEMBL4208204 | 0.67 | ALDH1A1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |