Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035748 | 0.86 | MMP1 (0.40) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL4035688 | 0.71 | CA12 (0.39) | MMP9CA2CA9CA12CA1 | |
| SCHEMBL4038954 | 0.71 | MMP3 (0.43) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL4032723 | 0.70 | MMP1 (0.61) | RAB9AMMP1MMP3MMP7MMP9 | |
| SCHEMBL4038524 | 0.68 | MMP2 (0.34) | MMP1MMP3MMP9CA9CA12 | |
| SCHEMBL4038496 | 0.68 | PSEN1 (0.39) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL4035864 | 0.68 | MEN1 (0.44) | SIGMAR1HTTHSD17B10MAPTDRD4 | |
| SCHEMBL4033428 | 0.64 | MMP1 (0.59) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL5634226 | 0.63 | MCHR1 (0.55) | RAB9AMMP1MMP3MMP7MMP9 | |
| SCHEMBL3937356 | 0.63 | ADAM17 (0.50) | MMP1MMP3MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |