Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4032958 | 0.73 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1NPSR1LMNA | |
| SCHEMBL4041586 | 0.72 | FKBP1A (0.41) | ALDH1A1NPSR1 | |
| SCHEMBL4038466 | 0.69 | ALDH1A1 (0.43) | ALDH1A1USP2KMT2AHTTMEN1 | |
| SCHEMBL4035235 | 0.67 | ALDH1A1 (0.76) | ALDH1A1USP2POLBKMT2AHTT | |
| SCHEMBL4033188 | 0.67 | ALDH1A1 (0.46) | ALDH1A1POLBKMT2AHTTKDM4E | |
| SCHEMBL4036533 | 0.64 | MMP3 (0.43) | ALDH1A1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL695071 | 0.64 | MMP2 (0.59) | ALDH1A1HTTMAPTNPSR1LMNA | |
| SCHEMBL17833176 | 0.64 | MMP2 (0.59) | ALDH1A1HTTMAPTNPSR1LMNA | |
| SCHEMBL8718942 | 0.63 | LMNA (0.58) | ALDH1A1USP2HTTMAPTHSD17B10 | |
| SCHEMBL4704780 | 0.61 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | disclosed |