Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 7/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041586 | 0.88 | FKBP1A (0.41) | ALDH1A1FKBP1AMMP1MMP9MMP13 | |
| SCHEMBL4033188 | 0.86 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL4038466 | 0.79 | ALDH1A1 (0.43) | ALDH1A1FKBP1AMMP1MMP9MMP13 | |
| SCHEMBL4038075 | 0.73 | ALDH1A1 (0.47) | ALDH1A1GAAMEN1KMT2ANPSR1 | |
| SCHEMBL4036533 | 0.71 | MMP3 (0.43) | ALDH1A1MMP1MMP9MMP13MMP3 | |
| SCHEMBL695071 | 0.70 | MMP2 (0.59) | ALDH1A1FKBP1ACYP3A4CYP2C19MMP9 | |
| SCHEMBL17833176 | 0.70 | MMP2 (0.59) | ALDH1A1FKBP1ACYP3A4CYP2C19MMP9 | |
| SCHEMBL7346677 | 0.70 | MMP1 (0.54) | ALDH1A1CYP3A4CYP2C19L3MBTL1MMP1 | |
| SCHEMBL8718942 | 0.69 | LMNA (0.58) | ALDH1A1FKBP1ACYP3A4CYP2C19MMP9 | |
| SCHEMBL4704780 | 0.67 | ALDH1A1 (0.46) | ALDH1A1FKBP1ACYP3A4CYP2C19L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |