Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 4/20 | 0.38 |
| ▸ | MMP9 | P14780 | 4/20 | 0.38 |
| ▸ | MMP13 | P45452 | 4/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP7 | P09237 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4032958 | 0.88 | ALDH1A1 (0.43) | FKBP1AALDH1A1MMP1MMP9MMP13 | |
| SCHEMBL4038466 | 0.76 | ALDH1A1 (0.43) | FKBP1AALDH1A1MMP1MMP9MMP13 | |
| SCHEMBL4033188 | 0.75 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL4038075 | 0.72 | ALDH1A1 (0.47) | ALDH1A1NPSR1 | |
| SCHEMBL4036533 | 0.70 | MMP3 (0.43) | ALDH1A1MMP1MMP9MMP13MMP3 | |
| SCHEMBL695071 | 0.70 | MMP2 (0.59) | FKBP1AALDH1A1MMP9NPSR1 | |
| SCHEMBL17833176 | 0.70 | MMP2 (0.59) | FKBP1AALDH1A1MMP9NPSR1 | |
| SCHEMBL8718942 | 0.69 | LMNA (0.58) | FKBP1AALDH1A1MMP9MAPK1NPSR1 | |
| SCHEMBL4704780 | 0.67 | ALDH1A1 (0.46) | FKBP1AALDH1A1MMP9NPSR1 | |
| SCHEMBL14843813 | 0.66 | MMP1 (0.52) | ALDH1A1MMP1MMP9MMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |