Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 4/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | MC3R | P41968 | 1/20 | 0.31 |
| ▸ | MC1R | Q01726 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | CTSK | P43235 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043435 | 0.93 | CTSK (0.38) | CHRNA7CHRNB2CHRNA4ALDH1A1KDM4E | |
| SCHEMBL4042524 | 0.91 | CHRNA7 (0.37) | CHRNA7CHRNB2CHRNA4ALDH1A1KDM4E | |
| SCHEMBL4046940 | 0.90 | KDM4E (0.35) | ALDH1A1KDM4EMAPTLMNANPSR1 | |
| SCHEMBL4043632 | 0.89 | CHRNA7 (0.40) | CHRNA7CHRNB2CHRNA4ALDH1A1MAPT | |
| SCHEMBL4047709 | 0.89 | ALDH1A1 (0.34) | CHRNA7ALDH1A1KDM4EMAPTNPSR1 | |
| SCHEMBL4047814 | 0.88 | CHRNB2 (0.36) | CHRNA7CHRNB2CHRNA4ALDH1A1KDM4E | |
| SCHEMBL4048801 | 0.85 | CTSK (0.39) | ALDH1A1KDM4ECTSSHPGDCTSK | |
| SCHEMBL4051394 | 0.85 | CTSK (0.34) | KDM4EUSP2CTSK | |
| SCHEMBL4046927 | 0.85 | CHRNA7 (0.41) | CHRNA7CHRNB2CHRNA4ALDH1A1KDM4E | |
| SCHEMBL4051965 | 0.84 | MC4R (0.38) | ALDH1A1KDM4EMAPTLMNARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |