Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | CTSV | O60911 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 2/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047585 | 0.93 | CTSK (0.41) | CTSSCTSVCTSLCTSKCHRNB2 | |
| SCHEMBL4046502 | 0.92 | PREP (0.34) | CTSSCTSKCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL4042344 | 0.90 | CTSK (0.33) | CTSKCHRNB2CHRNA7CHRNA4GAA | |
| SCHEMBL6215468 | 0.89 | CHRNB2 (0.40) | CTSSCTSVCTSLCTSKCHRNB2 | |
| SCHEMBL4049249 | 0.89 | CHRNB2 (0.36) | CTSSCTSVCTSLCHRNB2CHRNA7 | |
| SCHEMBL4041817 | 0.89 | CTSL (0.33) | CTSSCTSVCTSLCTSKPREP | |
| SCHEMBL4046671 | 0.85 | CTSK (0.41) | CTSSCTSVCTSLCTSK | |
| SCHEMBL4041842 | 0.84 | CHRNB2 (0.37) | CTSSCTSVCTSLCTSKCHRNB2 | |
| SCHEMBL4047097 | 0.83 | CTSL (0.33) | CTSSCTSVCTSLCTSKGAA | |
| SCHEMBL4039790 | 0.83 | CTSK (0.39) | CTSSCTSVCTSLCTSKCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |