Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CTSV | O60911 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6211058 | 0.91 | CHRNB2 (0.42) | CHRNB2CHRNA7CHRNA4GAACTSV | |
| SCHEMBL4042994 | 0.89 | CTSS (0.35) | CHRNB2CHRNA7CHRNA4GAACTSV | |
| SCHEMBL4045865 | 0.83 | CTSK (0.54) | CTSVCTSLCTSSCTSKLMNA | |
| SCHEMBL4047585 | 0.82 | CTSK (0.41) | CHRNB2CHRNA7CHRNA4CTSVCTSL | |
| SCHEMBL4043868 | 0.82 | CTSS (0.45) | CTSVCTSLCTSSCTSKTP53 | |
| SCHEMBL4046502 | 0.81 | PREP (0.34) | CHRNB2CHRNA7CHRNA4GAACTSS | |
| SCHEMBL8348382 | 0.81 | CTSK (0.57) | CHRNB2CHRNA7CHRNA4GAACTSS | |
| SCHEMBL4042344 | 0.80 | CTSK (0.33) | CHRNB2CHRNA7CHRNA4GAACTSK | |
| SCHEMBL6239332 | 0.80 | PREP (0.40) | CHRNB2CHRNA7CHRNA4CTSVCTSL | |
| SCHEMBL4041482 | 0.79 | CTSS (0.40) | CTSVCTSLCTSSCTSKMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |