Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 2/20 | 0.31 |
| ▸ | CTSL | P07711 | 2/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.31 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4042354 | 0.94 | TAS1R3 (0.37) | CTSVCTSLCTSSTAS1R3TAS1R1 | |
| SCHEMBL4043383 | 0.93 | TAS1R3 (0.35) | TAS1R3TAS1R1BCAT1L3MBTL1GAA | |
| SCHEMBL4043929 | 0.91 | CTSV (0.32) | CTSVCTSLCTSSTAS1R3TAS1R1 | |
| SCHEMBL4044402 | 0.90 | GAA (0.36) | TAS1R3TAS1R1GAAALDH1A1F2 | |
| SCHEMBL4043537 | 0.90 | PIK3CG (0.37) | POLBALDH1A1LMNASMN1; SMN2KCNQ1 | |
| SCHEMBL4048699 | 0.87 | CTSK (0.40) | CTSVCTSLCTSS | |
| SCHEMBL4042413 | 0.85 | CTSK (0.40) | CTSVCTSLCTSSTAS1R3TAS1R1 | |
| SCHEMBL4051242 | 0.84 | CTSK (0.33) | CTSVCTSLCTSS | |
| SCHEMBL4050896 | 0.84 | HPGD (0.34) | CTSVCTSLCTSSGAAALDH1A1 | |
| SCHEMBL4045043 | 0.84 | HPGD (0.38) | CTSVCTSLCTSSPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |