Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | MC3R | P41968 | 1/20 | 0.35 |
| ▸ | MC1R | Q01726 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4040539 | 0.94 | MC4R (0.41) | MC4RMC3RMC1RCTSKITGA4 | |
| SCHEMBL4045924 | 0.94 | USP30 (0.40) | MC4RMC3RMC1RITGA4ITGB7 | |
| SCHEMBL4043350 | 0.93 | HTRA1 (0.35) | FNTAFNTBMC4RMC3RMC1R | |
| SCHEMBL4041003 | 0.90 | CTSL (0.39) | CTSK | |
| SCHEMBL4045521 | 0.89 | CTSK (0.43) | CTSK | |
| SCHEMBL4052303 | 0.88 | CTSK (0.35) | MC4RMC3RMC1RCTSK | |
| SCHEMBL4043883 | 0.88 | CTSK (0.42) | FNTAFNTBMC4RMC3RMC1R | |
| SCHEMBL4042529 | 0.88 | BCL2 (0.38) | MC4RMC3RMC1RCTSKITGA4 | |
| SCHEMBL4044603 | 0.88 | MC4R (0.37) | FNTAFNTBMC4RMC3RMC1R | |
| SCHEMBL4044539 | 0.88 | ITGA4 (0.36) | FNTAFNTBCTSKACE2ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |