Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.33 |
| ▸ | CTSS | P25774 | 4/20 | 0.33 |
| ▸ | CTSK | P43235 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041595 | 0.90 | CTSK (0.42) | CTSLCTSSCTSK | |
| SCHEMBL6213000 | 0.89 | NPC1 (0.38) | CTSLCTSSCTSKLMNAGAA | |
| SCHEMBL4044596 | 0.89 | CTSL (0.38) | CTSLCTSSCTSKLMNAGAA | |
| SCHEMBL4042694 | 0.88 | CTSL (0.34) | CTSLCTSSCTSKGAA | |
| SCHEMBL4045681 | 0.85 | LMNA (0.36) | CTSLCTSSCTSKLMNAGAA | |
| SCHEMBL4043809 | 0.83 | L3MBTL1 (0.32) | GAA | |
| SCHEMBL4049041 | 0.83 | CHRNB2 (0.36) | LMNAGAA | |
| SCHEMBL4042598 | 0.82 | CTSK (0.31) | CTSK | |
| SCHEMBL4049252 | 0.82 | CTSK (0.39) | CTSLCTSSCTSK | |
| SCHEMBL4050428 | 0.82 | HPGD (0.33) | LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |