Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | USP2 | O75604 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | FPR1 | P21462 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4042598 | 0.90 | CTSK (0.31) | L3MBTL1 | |
| SCHEMBL4045681 | 0.89 | LMNA (0.36) | ALDH1A1USP2SMN1; SMN2GAAHPGD | |
| SCHEMBL4041595 | 0.86 | CTSK (0.42) | — | |
| SCHEMBL4044049 | 0.83 | CTSL (0.33) | GAA | |
| SCHEMBL4042694 | 0.82 | CTSL (0.34) | ALDH1A1SMN1; SMN2GAAKDM4EHSD17B10 | |
| SCHEMBL4049041 | 0.81 | CHRNB2 (0.36) | USP2SMN1; SMN2GAANPSR1HTT | |
| SCHEMBL4043622 | 0.81 | CTSK (0.39) | L3MBTL1ALDH1A1KDM4ECA12CA1 | |
| SCHEMBL4040779 | 0.81 | CTSV (0.34) | L3MBTL1ALDH1A1USP2SMN1; SMN2GAA | |
| SCHEMBL4045411 | 0.81 | PREP (0.33) | L3MBTL1ALDH1A1USP2SMN1; SMN2GAA | |
| SCHEMBL4044715 | 0.80 | MMP1 (0.34) | L3MBTL1ALDH1A1GAAKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |