Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 12/20 | 0.31 |
| ▸ | CTSS | P25774 | 6/20 | 0.31 |
| ▸ | CTSB | P07858 | 4/20 | 0.31 |
| ▸ | CTSL | P07711 | 9/20 | 0.31 |
| ▸ | CTSV | O60911 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047038 | 0.91 | CTSK (0.39) | CTSKCTSSCTSBCTSLCTSV | |
| SCHEMBL4042095 | 0.90 | CTSK (0.39) | NPC1RAB9ASMN1; SMN2CTSKCTSS | |
| SCHEMBL4047097 | 0.89 | CTSL (0.33) | NPC1RAB9ASMN1; SMN2TSHRCTSK | |
| SCHEMBL4040800 | 0.89 | PREP (0.36) | NPC1RAB9ASMN1; SMN2TSHRCTSK | |
| SCHEMBL4046215 | 0.89 | CHRNB2 (0.34) | SMN1; SMN2TSHRCTSKCTSSCTSB | |
| SCHEMBL4046790 | 0.89 | USP30 (0.36) | USP30CTSKCTSSCTSBCTSL | |
| SCHEMBL4050728 | 0.86 | SMN1; SMN2 (0.33) | SMN1; SMN2TSHRCTSKCTSSCTSB | |
| SCHEMBL4050878 | 0.86 | CTSK (0.38) | NPC1RAB9ASMN1; SMN2USP30CTSK | |
| SCHEMBL4042344 | 0.84 | CTSK (0.33) | SMN1; SMN2CTSKMAPTGAAPKM | |
| SCHEMBL4046064 | 0.84 | SMN1; SMN2 (0.35) | SMN1; SMN2CTSKCTSSCTSBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |