SCHEMBL404717

SCHEMBL404717

CCCCCC(CC)Oc1ccccc1C(Oc1nnncc1-c1ccccc1)c1ccccc1OC(CC)CCCCC

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 1/20 0.31
ADRA2A P08913 3/20 0.31
ADRA2B P18089 3/20 0.31
ADRA2C P18825 3/20 0.31
MAOA P21397 3/20 0.31
MAOB P27338 3/20 0.31
NISCH Q9Y2I1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21525741 0.84 SOAT1 (0.33) SOAT1
SCHEMBL118830 0.82 HTR1A (0.31) SOAT1
SCHEMBL19066395 0.82 HTR1A (0.31) SOAT1
SCHEMBL404719 0.78 PPARG (0.31)
SCHEMBL20607656 0.78 MCHR1 (0.32) ADRA2AADRA2BADRA2CNISCH
SCHEMBL25315299 0.77
SCHEMBL2709506 0.72 ALDH1A1 (0.35)
SCHEMBL14486011 0.71 SLC37A4 (0.32) SOAT1
SCHEMBL1697182 0.71 ADRA2A (0.33) ADRA2AADRA2BADRA2CMAOAMAOB
SCHEMBL12474663 0.71 HTR1A (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024106520-A1 NON-STICKY STABLE COMPOSITION WITH TEXTURE TRANSFORMATION PROPERTY L'OREAL (FR) 2024-05-23 WO claimed
EP-3393437-B1 PHOTOPROTECTIVE COMPOSITION BASED ON A CARBOXYLIC ACID ESTER; USE OF SAID COMPOUND FOR INCREASING THE SUN PROTECTION FACTOR OREAL (FR) 2023-06-07 EP claimed
US-10918583-B2 Cosmetic or dermatological composition comprising a merocyanine, an organic UVB-screening agent and an additional organic UVA-screening agent L'OREAL (FR) 2021-02-16 US claimed
EP-3193816-B1 COMPOSITION BASED ON MULTILAYER SPHERICAL COMPOSITE PARTICLES AND ON A UV-SCREENING AGENT OREAL (FR) 2020-05-13 EP claimed
US-20190336421-A1 COMPOSITION COMPRISING RESORCINOL OR DERIVATIVE THEREOF L'OREAL (FR) 2019-11-07 US claimed
EP-3197563-B1 COMPOSITION BASED ON A LIPOPHILIC ORGANIC UV-SCREENING AGENT AND A FILLER OREAL (FR) 2019-10-30 EP claimed
EP-2775994-B1 COMPOSITION WITH A CONTINUOUS OIL PHASE CONTAINING AT LEAST ONE LIPOPHILIC ORGANIC UV-SCREENING AGENT AND HYDROPHOBIC SILICA AEROGEL PARTICLES OREAL (FR) 2019-10-16 EP claimed
EP-3016631-B1 COSMETIC COMPOSITION OREAL (FR) 2019-10-02 EP claimed
US-10272021-B2 Composition based on multilayer spherical composite particles and on a UV-screening agent L'OREAL (FR) 2019-04-30 US claimed
EP-2999521-B1 SYNERGISTIC PHOTOPROTECTIVE COMPOSITIONS EDGEWELL PERSONAL CARE BRANDS LLC (US) 2019-01-09 EP claimed
WO-2013084184-A2 PHOTOPROTECTIVE AND SELF-TANNING COSMETIC EMULSIONS L'OREAL (FR) 2013-06-13 WO claimed
WO-2013068237-A1 COMPOSITION WITH A CONTINUOUS OIL PHASE CONTAINING AT LEAST ONE LIPOPHILIC ORGANIC UV-SCREENING AGENT AND HYDROPHOBIC SILICA AEROGEL PARTICLES L'OREAL (FR) 2013-05-16 WO claimed
US-20130058990-A1 COMPOSITION CONTAINING A DIBENZOYLMETHANE SCREENING AGENT AND A HYDROPHILIC OR WATER-SOLUBLE MEROCYANIN UV-SCREENING AGENT; PROCESS FOR PHOTOSTABILIZING THE DIBENZOYLMETHANE SCREENING AGENT L'OREAL (FR) 2013-03-07 US claimed
EP-2547313-A1 COMPOSITION CONTAINING A DIBENZOYLMETHANE SCREENING AGENT AND A HYDROPHILIC OR WATER-SOLUBLE MEROCYANIN UV-SCREENING AGENT; PROCESS FOR PHOTOSTABILIZING THE DIBENZOYLMETHANE SCREENING AGENT L'Oréal (FR) 2013-01-23 EP claimed
WO-2012168102-A2 ANHYDROUS ANTISUN CREAM COMPRISING A NON-EMULSIFYING ELASTOMERIC ORGANOPOLYSILOXANE, A MATTING AGENT AND A NON-SILICONE ORGANIC OIL THICKENER L'OREAL (FR) 2012-12-13 WO claimed
EP-2174644-B1 Cosmetic composition comprising a dibenzoylmethane derivative and a dithiolane; Photostabilization of a dibenzoylmethane derivative OREAL (FR) 2012-11-14 EP claimed
WO-2011113718-A1 COMPOSITION CONTAINING A DIBENZOYLMETHANE SCREENING AGENT AND A HYDROPHILIC OR WATER-SOLUBLE MEROCYANIN UV-SCREENING AGENT; PROCESS FOR PHOTOSTABILIZING THE DIBENZOYLMETHANE SCREENING AGENT L'OREAL (FR) 2011-09-22 WO claimed
US-20100172944-A1 COMBINATION OF MONOSACCHARIDES WITH SUNSCREENS AND USE THEREOF L'OREAL (FR) 2010-07-08 US claimed
US-20100086502-A1 Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor L'OREAL (FR) 2010-04-08 US claimed
US-20090285868-A1 Photostable cosmetic compositions comprising dibenzoylmethane/pyrrolidinone compounds L'OREAL (FR) 2009-11-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190336421-A1 COMPOSITION COMPRISING RESORCINOL OR DERIVATIVE THEREOF NQO1, LRAT, RBP4 SOAT1 489/4885ADRA2A 976/4885ADRA2B 1796/4885
US-20100086502-A1 Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor NOTUM, DDT, FDFT1 SOAT1 20/4885ADRA2A 4702/4885ADRA2B 4448/4885
US-20090285868-A1 Photostable cosmetic compositions comprising dibenzoylmethane/pyrrolidinone compounds NOTUM, CYP51A1, DHPS SOAT1 81/4885ADRA2A 4692/4885ADRA2B 4408/4885
US-10272021-B2 Composition based on multilayer spherical composite particles and on a UV-screening agent CUTA, RAD52, PSMC3 SOAT1 3955/4885ADRA2A 3103/4885ADRA2B 3073/4885
US-20130058990-A1 COMPOSITION CONTAINING A DIBENZOYLMETHANE SCREENING AGENT AND A HYDROPHILIC OR WATER-SOLUBLE MEROCYANIN UV-SCREENING AGENT; PROCESS FOR PHOTOSTABILIZING THE DIBENZOYLMETHANE SCREENING AGENT CRYZ, MSH6, TYR SOAT1 1427/4885ADRA2A 3380/4885ADRA2B 3472/4885
US-10918583-B2 Cosmetic or dermatological composition comprising a merocyanine, an organic UVB-screening agent and an additional organic UVA-screening agent KRT18, CRYZ, CUTA SOAT1 2475/4885ADRA2A 1331/4885ADRA2B 594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.