Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.40 |
| ▸ | CTSL | P07711 | 16/20 | 0.40 |
| ▸ | CTSS | P25774 | 12/20 | 0.40 |
| ▸ | CTSB | P07858 | 5/20 | 0.40 |
| ▸ | CTSV | O60911 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4038978 | 0.91 | USP30 (0.34) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4051635 | 0.91 | HPGD (0.37) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4041991 | 0.90 | CTSK (0.46) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4042533 | 0.90 | CTSK (0.40) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4048699 | 0.90 | CTSK (0.40) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4043432 | 0.89 | KCNQ1 (0.38) | HPGDTRPM8 | |
| SCHEMBL4043865 | 0.88 | CTSK (0.36) | CTSKCTSLCTSSCTSBHPGD | |
| SCHEMBL4043593 | 0.87 | USP2 (0.33) | CTSKTRPM8 | |
| SCHEMBL4044402 | 0.87 | GAA (0.36) | TRPM8 | |
| SCHEMBL4045350 | 0.86 | CHRNB2 (0.34) | CTSKHPGDTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |