Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ1 | P51787 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046322 | 0.91 | CHRNB2 (0.38) | KCNQ1KMT2ACHRNB2CHRNA7CHRNA4 | |
| SCHEMBL4045350 | 0.91 | CHRNB2 (0.34) | KMT2AMEN1CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL4047148 | 0.90 | CHRNB2 (0.39) | KCNQ1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4044402 | 0.90 | GAA (0.36) | KCNQ1USP2GAAALDH1A1TRPM8 | |
| SCHEMBL4043537 | 0.90 | PIK3CG (0.37) | KCNQ1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4043869 | 0.90 | KCNQ1 (0.37) | KCNQ1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4049501 | 0.89 | CTSK (0.40) | HPGDTRPM8 | |
| SCHEMBL4044847 | 0.87 | CHRNB2 (0.39) | CHRNB2CHRNA7CHRNA4GAAALDH1A1 | |
| SCHEMBL4051635 | 0.86 | HPGD (0.37) | GAAALDH1A1HPGDTRPM8USP30 | |
| SCHEMBL4038978 | 0.86 | USP30 (0.34) | HPGDTRPM8USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |