SCHEMBL4055332

SCHEMBL4055332

Cc1cc2scnc2cc1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.41
RAB9A P51151 7/20 0.41
KDM4E B2RXH2 4/20 0.41
TDP1 Q9NUW8 2/20 0.41
HKDC1 Q2TB90 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALDH1A1 P00352 6/20 0.38
HSD17B10 Q99714 2/20 0.38
MAPT P10636 4/20 0.37
MAPK1 P28482 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
HPGD P15428 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
G6PD P11413 1/20 0.37
CYP2C9 P11712 1/20 0.37
PKM P14618 1/20 0.37
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13734473 0.92 NPC1 (0.41) NPC1RAB9AKDM4ETDP1HKDC1
SCHEMBL4048510 0.83 GAA (0.45) NPC1RAB9AKDM4ETDP1HKDC1
SCHEMBL6031739 0.83 NPC1 (0.46) NPC1RAB9AKDM4ETDP1HKDC1
SCHEMBL30093444 0.83 GAA (0.45) NPC1RAB9AKDM4ETDP1HKDC1
SCHEMBL11795684 0.81 ALDH1A1 (0.45) NPC1RAB9AKDM4ETDP1ALDH1A1
SCHEMBL720130 0.76 ALDH1A1 (0.38) NPC1RAB9AKDM4ETDP1HKDC1
SCHEMBL30089784 0.76 ALDH1A1 (0.38) NPC1RAB9AKDM4ETDP1HKDC1
SCHEMBL4052274 0.76 RIPK2 (0.39) NPC1RAB9AKDM4ETDP1HKDC1
SCHEMBL21155441 0.76 DYRK1A (0.42) NPC1RAB9AKDM4ETDP1HKDC1
SCHEMBL2999828 0.76 TERT (0.45) NPC1RAB9AKDM4ETDP1HKDC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0271260-B1 Supersensitization of silver halide emulsions MINNESOTA MINING & MFG (US) 1995-01-04 EP claimed
US-4873184-A ADDITION OF A METAL COMPLEXING AGENT TO THE EMULSION; HIGH SPEED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-10 US claimed
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 EP claimed
US-20230227474-A1 COMPOSITIONS AND METHODS FOR CORRECTION OF ABERRANT SPLICING SKYHAWK THERAPEUTICS, INC. (US) 2023-07-20 US disclosed
US-20230069804-A1 METHODS AND COMPOSITIONS FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. 2023-03-02 US disclosed
US-20220048890-A1 METHODS AND COMPOSITIONS FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. 2022-02-17 US disclosed
EP-2570418-A2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-03-20 EP disclosed
EP-1555267-B1 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES OTSUKA PHARMA CO LTD (JP) 2013-01-16 EP disclosed
CN-101124516-B Pattern forming material, pattern forming apparatus, and pattern forming method FUJI PHOTO FILM CO LTD 2012-01-18 CN disclosed
US-7598026-B2 Image forming method using a silver halide color photographic light-sensitive material, and silver halide color photographic light-sensitive material FUJIFILM CORPORATION (JP) 2009-10-06 US disclosed
EP-1211555-B1 Silver halide photographic emulsion and silver halide photographic material containing said silver halide photographic emulsion FUJIFILM CORP (JP) 2008-12-31 EP disclosed
US-4030927-A PHOTOGRAPHIC SILVER HALIDE EMULSIONS FUJI PHOTO FILM CO., LTD. (JA) 1977-06-21 US disclosed
US-4002480-A CONTAINING A DINUCLEAR MEROCYANINE SENSITIZING DYE AND AN ANTIFOGGING AGENT FUJI PHOTO FILM CO., LTD. (JA) 1977-01-11 US disclosed
US-3988155-A CYANINE SENSITIZING DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-10-26 US disclosed
US-3986878-A SILVER HALIDE PHOTOGRAPHIC EMULSION FUJI PHOTO FILM CO., LTD. (JA) 1976-10-19 US disclosed
US-3985563-A Silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-10-12 US disclosed
US-3976492-A CYANINE DYE SENSITIZERS FUJI PHOTO FILM CO., LTD. (JA) 1976-08-24 US disclosed
US-3955996-A Method for spectrally sensitizing photographic light-sensitive emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-05-11 US disclosed
US-3953215-A X-RAY FILM FUJI PHOTO FILM CO., LTD. (JA) 1976-04-27 US disclosed
US-3951666-A CYANINE AND MEROCYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220048890-A1 METHODS AND COMPOSITIONS FOR MODULATING SPLICING RBM17, SF3B1, SF3B5 NPC1 2066/4885RAB9A 2924/4885KDM4E 2544/4885
US-20230227474-A1 COMPOSITIONS AND METHODS FOR CORRECTION OF ABERRANT SPLICING RBM17, SF3B1, SF3B5 NPC1 1934/4885RAB9A 1892/4885KDM4E 2588/4885
US-20230069804-A1 METHODS AND COMPOSITIONS FOR MODULATING SPLICING RBM17, SF3B1, SF3B5 NPC1 2066/4885RAB9A 2924/4885KDM4E 2544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.