Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CMA1 | P23946 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8012376 | 0.85 | ELANE (0.43) | ELANECTSLCTSBCTSK | |
| SCHEMBL3229202 | 0.73 | CHRNB2 (0.47) | — | |
| SCHEMBL4234591 | 0.72 | CCR2 (0.31) | CCR2 | |
| SCHEMBL3224952 | 0.68 | HRH4 (0.45) | — | |
| SCHEMBL22138808 | 0.67 | DPP4 (0.40) | — | |
| SCHEMBL24425245 | 0.66 | CTSV (0.47) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL27348836 | 0.66 | NR1I2 (0.34) | CTSL | |
| SCHEMBL4052407 | 0.65 | DPP4 (0.50) | — | |
| SCHEMBL3226083 | 0.65 | DPP4 (0.50) | — | |
| SCHEMBL16474261 | 0.65 | CASP1 (0.44) | CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111680-A1 | TRPV4 ANTAGONISTS | SMITHLINE BEECHAM CORPORATION (US) | 2009-09-11 | — | — | WO | disclosed |