Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9084531 | 0.78 | LMNA (0.48) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL14782540 | 0.77 | LMNA (0.52) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL439716 | 0.74 | LMNA (0.59) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL423183 | 0.74 | PDE2A (0.61) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL578033 | 0.74 | CYP1A2 (0.41) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL8656719 | 0.72 | LMNA (0.48) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL6386090 | 0.72 | LMNA (0.48) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL401292 | 0.72 | LMNA (0.54) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL401293 | 0.72 | CYP1A2 (0.48) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL8886934 | 0.72 | LMNA (0.48) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547713-B2 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | GU LIANQUAN | 2009-06-16 | — | — | US | claimed |
| US-20060111405-A1 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | GU LIANQUAN | 2006-05-25 | — | — | US | claimed |
| US-7547713-B2 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | GU LIANQUAN | 2009-06-16 | — | — | US | disclosed |
| US-20060111405-A1 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | GU LIANQUAN | 2006-05-25 | — | — | US | disclosed |
| US-5723410-A | PLANT GROWTH REGULATORS AND HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-03-03 | — | — | US | disclosed |
| EP-0511993-A1 | HERBICIDAL SULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-11-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111405-A1 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | PTGS2, PTGES2, PTGES | LMNA 3323/4885SMN1; SMN2 3704/4885L3MBTL1 4791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.