SCHEMBL4062953

SCHEMBL4062953

CCC(N(C)C)N1CCNCC1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 7/20 0.34
OPRM1 P35372 3/20 0.34
SLC6A2 P23975 3/20 0.33
SLC6A4 P31645 3/20 0.33
CHRM5 P08912 1/20 0.32
CHRM3 P20309 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19920792 0.88 SLC6A2 (0.31) OPRD1OPRM1SLC6A2SLC6A4
SCHEMBL27699520 0.84
SCHEMBL10916513 0.83 SLC6A4 (0.34) OPRD1OPRM1SLC6A2SLC6A4
SCHEMBL29905540 0.79
SCHEMBL29614428 0.76 OPRD1 (0.34) OPRD1OPRM1
SCHEMBL5377836 0.76
SCHEMBL11552775 0.74 ALDH1A1 (0.37) SLC6A2SLC6A4MEN1KMT2A
SCHEMBL1856620 0.74
SCHEMBL232544 0.74
SCHEMBL7720694 0.73 SLC6A2 (0.38) OPRD1OPRM1SLC6A2SLC6A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103333156-B Preparation method of 2-substituted arylethenyl-N-methylated quinoline derivative and application of 2-substituted arylethenyl-N-methylated quinoline derivative in preparation of drug for treating Alzheimer disease UNIV SUN YAT SEN 2015-03-11 CN claimed
CN-103333156-A Preparation method of 2-substituted arylethenyl-N-methylated quinoline derivative and application of 2-substituted arylethenyl-N-methylated quinoline derivative in preparation of drug for treating Alzheimer disease UNIV ZHONGSHAN 2013-10-02 CN claimed
US-12559593-B2 Dual cure sealants PRC-DESOTO INTERNATIONAL, INC. (CA) 2026-02-24 US disclosed
US-11819550-B2 Liquid protein formulations containing cyclic adenosine monophosphate (cAMP) or adenosine triphosphate (ATP) EAGLE BIOLOGICS, INC. (US) 2023-11-21 US disclosed
EP-4272763-A2 LIQUID PROTEIN FORMULATIONS CONTAINING ORGANOPHOSPHATES Eagle Biologics, Inc. (US) 2023-11-08 EP disclosed
US-20230242710-A1 Dual Cure Sealants PRC-DESOTO INTERNATIONAL, INC. (US) 2023-08-03 US disclosed
EP-3043772-B1 LIQUID PROTEIN FORMULATIONS CONTAINING ORGANOPHOSPHATES EAGLE BIOLOGICS INC (US) 2023-07-19 EP disclosed
US-11655340-B2 Dual cure sealants PRC-DESOTO INTERNATIONAL, INC. (US) 2023-05-23 US disclosed
US-11471479-B2 Polysaccharide and nucleic acid formulations containing viscosity-lowering agents EAGLE BIOLOGICS, INC. (US) 2022-10-18 US disclosed
CN-110719928-B Dual cure sealant PRC-迪索托国际公司 2022-08-12 CN disclosed
CN-111202711-B Liquid protein formulations comprising organophosphates 伊戈尔生物药品股份有限公司 2022-06-21 CN disclosed
US-20030203926-A1 Anilinopyrimidine derivatives as IKK inhibitors and compositions and methods related thereto SIGNAL PHARMACEUTICALS, LLC 2003-10-30 US disclosed
EP-1349841-A2 ANILINOPYRIMIDINE DERIVATIVES AS IKK INHIBITORS AND COMPOSITIONS AND METHODS RELATED THERETO SIGNAL PHARMACEUTICALS, INC. (US) 2003-10-08 EP disclosed
EP-1349840-A2 ANILINOPYRIMIDINE DERIVATIVES AS JNK PATHWAY INHIBITORS AND COMPOSITIONS AND METHODS RELATED THERETO SIGNAL PHARMACEUTICALS, INC. (US) 2003-10-08 EP disclosed
US-20030008863-A1 Novel tricyclic diazepines tocolytic oxytocin receptor antagonists WYETH 2003-01-09 US disclosed
US-20030004159-A1 Novel cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists WYETH 2003-01-02 US disclosed
WO-2002083678-A1 TRICYCLIC DIAZEPINES AS TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS WYETH (US) 2002-10-24 WO disclosed
WO-2002083682-A1 NOVEL 10-CYCLOHEXENYL-PHENYL PYRROLOBENZODIAZEPINE-3-CARBOXAMIDES AND DERIVATIVES THEREOF; TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS WYETH (US) 2002-10-24 WO disclosed
WO-2002046171-A2 ANILINOPYRIMIDINE DERIVATIVES AS IKK INHIBITORS AND COMPOSITIONS AND METHODS RELATED THERETO SIGNAL PHARMACEUTICALS, INC. (US) 2002-06-13 WO disclosed
WO-2002046170-A2 ANILINOPYRIMIDINE DERIVATIVES AS JNK PATHWAY INHIBITORS AND COMPOSITIONS AND METHODS RELATED THERETO SIGNAL PHARMACEUTICALS, INC. (US) 2002-06-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11471479-B2 Polysaccharide and nucleic acid formulations containing viscosity-lowering agents RNGTT, SNRPA, SNRNP200 OPRD1 3459/4885OPRM1 3020/4885SLC6A2 2428/4885
US-11819550-B2 Liquid protein formulations containing cyclic adenosine monophosphate (cAMP) or adenosine triphosphate (ATP) PDE7A, PDE8A, PDE8B OPRD1 4404/4885OPRM1 4000/4885SLC6A2 2704/4885
US-20030008863-A1 Novel tricyclic diazepines tocolytic oxytocin receptor antagonists OXTR, OPRL1, HCRTR2 OPRD1 9/4885OPRM1 45/4885SLC6A2 2731/4885
US-20030203926-A1 Anilinopyrimidine derivatives as IKK inhibitors and compositions and methods related thereto NFKBIA, IKBKB, IKBKE OPRD1 1817/4885OPRM1 3333/4885SLC6A2 4826/4885
US-12559593-B2 Dual cure sealants DUOX2, DUOX1, GPX4 OPRD1 312/4885OPRM1 709/4885SLC6A2 4244/4885
US-20030004159-A1 Novel cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists OXTR, OPRL1, HCRTR2 OPRD1 10/4885OPRM1 49/4885SLC6A2 3323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.