Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MARS1 | P56192 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4062616 | 0.90 | SORT1 (0.37) | SORT1MRGPRX4MAPTPOLBSMN1; SMN2 | |
| SCHEMBL31448207 | 0.90 | SORT1 (0.37) | SORT1MRGPRX4MAPTPOLBSMN1; SMN2 | |
| SCHEMBL5388413 | 0.79 | GAA (0.37) | GAAATMKMT2AL3MBTL1GLA | |
| SCHEMBL4679224 | 0.74 | P2RX7 (0.33) | MAPTSMN1; SMN2GAAATMKMT2A | |
| SCHEMBL4682095 | 0.74 | PKM (0.34) | SMN1; SMN2GAAATMKMT2AMEN1 | |
| SCHEMBL7116484 | 0.74 | GAA (0.32) | SMN1; SMN2GAAATMKMT2AL3MBTL1 | |
| SCHEMBL7018877 | 0.74 | GAA (0.32) | SMN1; SMN2GAAATMKMT2AL3MBTL1 | |
| SCHEMBL4682067 | 0.74 | SMN1; SMN2 (0.35) | SMN1; SMN2GAAATMKMT2AKDM4E | |
| SCHEMBL4680432 | 0.74 | PPARG (0.41) | HPGDKDM4E | |
| SCHEMBL6794821 | 0.73 | PPOX (0.44) | MAPTGAAATMKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1226127-B1 | SUBSTITUTED PHENYL SULFAMOYL CARBOXAMIDES | BASF SE (DE) | 2009-07-01 | — | — | EP | disclosed |
| US-6849618-B2 | Uracil substituted phenyl sulfamoly carboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2005-02-01 | — | — | US | disclosed |
| US-20040220172-A1 | Herbicidal compositions for the desiccation/ defoliation of plants | CARLSEN MARIANNE | 2004-11-04 | — | — | US | disclosed |
| CN-1171875-C | Uracil substituted phenyl sulfamoyl carboxamides | �����ɷ� | 2004-10-20 | — | — | CN | disclosed |
| US-6689773-B2 | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-02-10 | — | — | US | disclosed |
| US-20030224941-A1 | Uracil substituted phenyl sulfamoyl carboxamides | CARLSEN MARIANNE (US) | 2003-12-04 | — | — | US | disclosed |
| US-6534492-B2 | Herbicidal phenylsulfamoyl carboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-18 | — | — | US | disclosed |
| CN-1383425-A | Uracil substituted phenyl sulfamoyl carboxamides | BASF AG (DE) | 2002-12-04 | — | — | CN | disclosed |
| EP-1226127-A2 | URACIL SUBSTITUTED PHENYL SULFAMOYL CARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-31 | — | — | EP | disclosed |
| US-20020045550-A1 | Uracil substituted phenyl sulfamoyl carboxamides | INTELLECTUAL PROPERTY DEPARTMENT BASF AKTIENGESELLSCHAFT (DE) | 2002-04-18 | — | — | US | disclosed |
| WO-2001083459-A2 | URACIL SUBSTITUTED PHENYL SULFAMOYL CARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045550-A1 | Uracil substituted phenyl sulfamoyl carboxamides | CCNH, CBR3, UNG | SORT1 4699/4885MRGPRX4 3194/4885MAPT 4524/4885 |
| US-20030224941-A1 | Uracil substituted phenyl sulfamoyl carboxamides | CCNH, CBR3, UNG | SORT1 4699/4885MRGPRX4 3194/4885MAPT 4524/4885 |
| US-20040220172-A1 | Herbicidal compositions for the desiccation/ defoliation of plants | CBR3, HDHD5, DDAH1 | SORT1 4761/4885MRGPRX4 2837/4885MAPT 4629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.