Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4084189 | 0.82 | HRH3 (0.40) | OPRM1OPRL1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL4075032 | 0.81 | HPGD (0.40) | OPRM1OPRL1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL4084407 | 0.81 | L3MBTL1 (0.40) | OPRM1OPRL1MEN1KMT2AL3MBTL1 | |
| SCHEMBL4080673 | 0.81 | HPGD (0.35) | OPRM1OPRL1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL206456 | 0.80 | POLB (0.45) | HPGDRAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL5162372 | 0.80 | RAB9A (0.43) | OPRM1OPRL1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL4084293 | 0.80 | HDAC3 (0.42) | OPRM1OPRL1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL206402 | 0.79 | ALDH1A1 (0.41) | OPRM1OPRL1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL208660 | 0.79 | PLAAT3 (0.46) | OPRM1OPRL1RAB9ASMN1; SMN2 | |
| SCHEMBL4085357 | 0.79 | L3MBTL1 (0.38) | OPRM1OPRL1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |