SCHEMBL4082431

SCHEMBL4082431

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nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CTSS P25774 3/20 0.38
CTSK P43235 1/20 0.38
ENPEP Q07075 5/20 0.36
CTSL P07711 2/20 0.35
ALDH1A1 P00352 1/20 0.35
TERT O14746 1/20 0.34
MME P08473 2/20 0.34
ACE P12821 2/20 0.34
CPA1 P15085 2/20 0.34
ACE2 Q9BYF1 2/20 0.34
CTSB P07858 1/20 0.34
DPP4 P27487 2/20 0.33
DPP8 Q6V1X1 2/20 0.33
DPP9 Q86TI2 2/20 0.33
DPP7 Q9UHL4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10718818 0.85 TERT (0.43) TERTMMEACECPA1ACE2
SCHEMBL23071543 0.85 TERT (0.43) TERTMMEACECPA1ACE2
SCHEMBL10718813 0.85 TERT (0.43) TERTMMEACECPA1ACE2
SCHEMBL23071542 0.85 TERT (0.43) TERTMMEACECPA1ACE2
SCHEMBL8526546 0.84 ALDH1A1 (0.46) ENPEPALDH1A1MMEACECPA1
SCHEMBL31174309 0.84 ALDH1A1 (0.46) ENPEPALDH1A1MMEACECPA1
SCHEMBL8526548 0.84 ALDH1A1 (0.46) ENPEPALDH1A1MMEACECPA1
SCHEMBL30272494 0.83 ALDH1A1 (0.50) ENPEPALDH1A1
SCHEMBL4099835 0.83 TERT (0.40) CTSSCTSKTERTMMEACE
SCHEMBL4086885 0.80 ENPEP (0.31) ENPEPTERTDPP4DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8076285-B2 Lysobactin amides AICURIS GMBH & CO. KG (DE) 2011-12-13 US disclosed
US-20090203582-A1 LYSOBACTIN AMIDES BAYER HEALTHCARE AG (DE) 2009-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203582-A1 LYSOBACTIN AMIDES AADAT, HAMP, DLST CTSS 660/4885CTSK 1058/4885ENPEP 61/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.