SCHEMBL4086885

SCHEMBL4086885

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nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ENPEP Q07075 9/20 0.31
DPP4 P27487 1/20 0.31
DPP8 Q6V1X1 1/20 0.31
DPP9 Q86TI2 1/20 0.31
PDCD1LG2 Q9BQ51 1/20 0.30
CD274 Q9NZQ7 1/20 0.30
CTSC P53634 1/20 0.30
TERT O14746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2181799 0.89 CTSC (0.34) DPP4DPP8DPP9PDCD1LG2CD274
SCHEMBL4087537 0.88 TERT (0.38) TERT
SCHEMBL4087536 0.88 TERT (0.38) TERT
SCHEMBL4082431 0.80 CTSS (0.38) ENPEPDPP4DPP8DPP9TERT
SCHEMBL4086999 0.79 TERT (0.38) DPP4DPP8DPP9TERT
SCHEMBL30272494 0.79 ALDH1A1 (0.50) ENPEP
SCHEMBL4094118 0.77 ENPEP (0.42) ENPEP
SCHEMBL4094111 0.77 ENPEP (0.42) ENPEP
SCHEMBL2193153 0.77 ENPEP (0.40) ENPEPDPP4DPP8DPP9CTSC
SCHEMBL9797953 0.77 DPP4 (0.38) ENPEPDPP4DPP8DPP9TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8076285-B2 Lysobactin amides AICURIS GMBH & CO. KG (DE) 2011-12-13 US disclosed
US-20090203582-A1 LYSOBACTIN AMIDES BAYER HEALTHCARE AG (DE) 2009-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203582-A1 LYSOBACTIN AMIDES AADAT, HAMP, DLST ENPEP 61/4885DPP4 552/4885DPP8 1169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.