SCHEMBL4088531

SCHEMBL4088531

CC(C)(C)Cc1ccccc1[C]=O

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 2/20 0.43
GABRA1 P14867 2/20 0.32
GABRB2 P47870 2/20 0.32
ESR1 P03372 1/20 0.30
SLC6A2 P23975 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17103519 0.80 RIPK1 (0.32) RIPK1GABRA1GABRB2
SCHEMBL3811212 0.79
SCHEMBL6680931 0.79 TSHR (0.45) RIPK1SLC6A2
SCHEMBL535892 0.78 GABRA1 (0.45) GABRA1GABRB2
SCHEMBL6685097 0.77 RIPK1 (0.56) RIPK1GABRA1GABRB2ESR1SLC6A2
SCHEMBL6685032 0.73 RIPK1 (0.48) RIPK1GABRA1GABRB2ESR1SLC6A2
SCHEMBL910448 0.72 DAO (0.38) GABRA1GABRB2
SCHEMBL3644028 0.71 PNMT (0.44) GABRA1GABRB2TAAR1
SCHEMBL9317847 0.71 FFAR1 (0.31) GABRA1GABRB2
SCHEMBL873220 0.71 FFAR1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US disclosed
US-9894901-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-20 US disclosed
US-9872493-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-23 US disclosed
US-20150305332-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-29 US disclosed
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-20150289512-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-20150282482-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-08 US disclosed
EP-2926660-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company Limited (JP) 2015-10-07 EP disclosed
EP-2923573-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company Limited (JP) 2015-09-30 EP disclosed
EP-2923574-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company Limited (JP) 2015-09-30 EP disclosed
CN-104902749-A Method for promoting plant growth SUMITOMO CHEMICAL CO 2015-09-09 CN disclosed
CN-104902750-A Method for promoting plant growth SUMITOMO CHEMICAL CO 2015-09-09 CN disclosed
CN-104902752-A Method for promoting plant growth SUMITOMO CHEMICAL CO 2015-09-09 CN disclosed
US-8445516-B2 Pharmaceutical composition for promoting angiogenesis OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-05-21 US disclosed
US-20090187025-A1 Pharmaceutical composition for promoting angiogenesis OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2009-07-23 US disclosed
CN-100473383-C Pharmaceutical composition for promoting angiogenesis OTSUKA PHARMA CO LTD (JP) 2009-04-01 CN disclosed
EP-1708705-B1 USE OF PIPERIDINE DERIVATIVES FOR PROMOTING ANGIOGENESIS OTSUKA PHARMA CO LTD (JP) 2009-02-18 EP disclosed
CN-1905877-A Pharmaceutical composition for promoting angiogenesis OTSUKA PHARMA CO LTD (JP) 2007-01-31 CN disclosed
EP-1708705-A1 PHARMACEUTICAL COMPOSITION FOR PROMOTING ANGIOGENESIS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-10-11 EP disclosed
WO-2005072734-A1 PHARMACEUTICAL COMPOSITION FOR PROMOTING ANGIOGENESIS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-08-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090187025-A1 Pharmaceutical composition for promoting angiogenesis FLT1, FLT4, KDR RIPK1 4391/4885GABRA1 937/4885GABRB2 1178/4885
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH FGF2, BROX, BOLA2; BOLA2B RIPK1 3959/4885GABRA1 981/4885GABRB2 525/4885
US-20150305332-A1 METHOD FOR PROMOTING PLANT GROWTH FGF1, BROX, FGF2 RIPK1 3628/4885GABRA1 1009/4885GABRB2 1171/4885
US-20150282482-A1 METHOD FOR PROMOTING PLANT GROWTH BOLA2; BOLA2B, BROX, TET1 RIPK1 3571/4885GABRA1 823/4885GABRB2 337/4885
US-20150289512-A1 METHOD FOR PROMOTING PLANT GROWTH FGF1, MKI67, FGF2 RIPK1 3305/4885GABRA1 3758/4885GABRB2 4003/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.