Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Medronic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.34 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Medronic Acid SCHEMBL5272656 | 0.96 | LMNA (0.33) | LMNABTN3A1SLC34A1 | |
| Medronic Acid SCHEMBL2801380 | 0.91 | SLC34A1 (0.33) | BTN3A1SLC34A1KDM4EMMP2THRB | |
| Medronic Acid SCHEMBL5423104 | 0.91 | SLC34A1 (0.33) | BTN3A1SLC34A1KDM4EMMP2THRB | |
| Medronic Acid SCHEMBL556782 | 0.91 | SLC34A1 (0.33) | BTN3A1SLC34A1KDM4EMMP2THRB | |
| Medronic Acid SCHEMBL8712850 | 0.91 | SLC34A1 (0.33) | BTN3A1SLC34A1KDM4EMMP2THRB | |
| Medronic Acid SCHEMBL8712848 | 0.91 | SLC34A1 (0.33) | BTN3A1SLC34A1KDM4EMMP2THRB | |
| Medronic Acid SCHEMBL27529621 | 0.91 | SLC34A1 (0.33) | BTN3A1SLC34A1KDM4EMMP2THRB | |
| Medronic Acid SCHEMBL9645616 | 0.91 | SLC34A1 (0.33) | BTN3A1SLC34A1KDM4EMMP2THRB | |
| Medronic Acid SCHEMBL5267588 | 0.91 | SLC34A1 (0.43) | BTN3A1SLC34A1KDM4EMMP2THRB | |
| Medronic Acid SCHEMBL7753674 | 0.91 | SLC34A1 (0.33) | BTN3A1SLC34A1KDM4EMMP2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119143096-A | Calcium carbonate/calcium phosphate composite hollow nanosphere and preparation method and application thereof | 西安交通大学 | 2024-12-17 | — | — | CN | claimed |
| CN-117187915-A | Normal-temperature nickel-free hole sealing agent and nickel-free hole sealing process | 佛山市海化表面处理科技有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-113562857-B | Salt inhibitor for salt-containing wastewater back-spraying quenching tower process and use method thereof | 上海丰信环保科技有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-112079455-B | Oilfield chemical scale inhibitor and preparation method and application thereof | 中国石油天然气股份有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-115814956-A | Beneficiation method for low-grade spodumene ores | 江西理工大学 | 2023-03-21 | — | — | CN | claimed |
| CN-115806806-A | Drilling fluid stuck releasing agent based on vermicular micelle acid and preparation method and use method thereof | 中石化石油工程技术服务有限公司 | 2023-03-17 | — | — | CN | claimed |
| CN-115466525-B | Flame-retardant reactive dye and preparation method thereof | 山东理工大学 | 2023-02-28 | — | — | CN | claimed |
| CN-115679334-A | Neutralizing and reducing agent for PCB (printed circuit board) glue removal post-treatment | 广东利尔化学有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-115636591-A | Glass frosting powder and glass frosting liquid | 深圳市海风润滑技术有限公司 | 2023-01-24 | — | — | CN | claimed |
| CN-115636517-A | Preparation method and application of scale-inhibiting type composite alkali | 杭州佑华环保科技有限公司 | 2023-01-24 | — | — | CN | claimed |
| CN-1351105-A | Corrosion inhibitor for cooling liquid of IC engine | NAVY ENGINEERING UNIV PLA (CN) | 2002-05-29 | — | — | CN | claimed |
| CN-1064752-C | Organic anti-scale corrosion inhibitor and its compounding process | URUMQI INST OF BOILER & PRESSU (CN) | 2001-04-18 | — | — | CN | claimed |
| CN-1258649-A | Recompounded multielement antisludging corrosion inhibitor | INST BEIJING YANSHAN PETROCHEM (CN) | 2000-07-05 | — | — | CN | claimed |
| CN-1041002-C | Corrosion inhibitor for coolant of diesel locomotives | ZHANG YOUXING (CN) | 1998-12-02 | — | — | CN | claimed |
| CN-1160847-A | Organic anti-scale corrosion inhibitor and its compounding process | URUMQI INST OF BOILER & PRESSU (CN) | 1997-10-01 | — | — | CN | claimed |
| CN-1031254-C | Stable sodium percarbonate and its prepn. method | UNIV SHANDONG (CN) | 1996-03-13 | — | — | CN | claimed |
| CN-1109030-A | Corrosion inhibitor for coolant of diesel locomotives | ZHANG YOUXING (CN) | 1995-09-27 | — | — | CN | claimed |
| CN-1098123-A | With polyacrylate and phosphonate is the dispersion agent/liquid agent composition of principal constituent | PROTEX MANUF PROD CHIMIQ (FR) | 1995-02-01 | — | — | CN | claimed |
| CN-1021650-C | Method for stabilizing concrete residues | SANDOZ LTD (CH) | 1993-07-21 | — | — | CN | claimed |
| US-4436721-A | Oral composition having mole ratio of tetra (methylene phosphonate) to alkali metal fluoride of at least 1.4:1 | COLGATE-PALMOLIVE COMPANY (US) | 1984-03-13 | — | — | US | claimed |