Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2266737 | 0.84 | TRPV4 (0.36) | TDP2NSD2HSP90AA1PAX8TDP1 | |
| SCHEMBL8654404 | 0.79 | TDP2 (0.42) | TDP2NSD2HSP90AA1PAX8TDP1 | |
| SCHEMBL9522846 | 0.78 | ALDH1A1 (0.42) | TDP1ALDH1A1HSD17B10LMNAMEN1 | |
| SCHEMBL1500713 | 0.77 | ALDH1A1 (0.40) | TDP1ALDH1A1HSD17B10KEAP1NFE2L2 | |
| SCHEMBL1021882 | 0.77 | KMT2A (0.44) | TDP1ALDH1A1HSD17B10LMNAGAA | |
| SCHEMBL2263745 | 0.77 | RAPGEF4 (0.40) | LMNAGAAMAPK1HTTCYP19A1 | |
| SCHEMBL29451557 | 0.76 | TSHR (0.47) | TDP1ALDH1A1HSD17B10GAATSHR | |
| SCHEMBL10538992 | 0.76 | TSHR (0.47) | TDP1ALDH1A1HSD17B10GAATSHR | |
| SCHEMBL8764002 | 0.76 | TSHR (0.47) | TDP1ALDH1A1HSD17B10LMNAGAA | |
| SCHEMBL2929807 | 0.75 | CA2 (0.41) | TDP2NSD2HSP90AA1PAX8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263598-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2012-09-11 | — | — | US | disclosed |
| US-20090186899-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-07-23 | — | — | US | disclosed |
| EP-0078498-B1 | METHOD FOR PROTECTING AMINO GROUP AND RESTORING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 1986-01-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186899-A1 | Substituted Sulfonamide Compounds | BDKRB1, BDKRB2, NPSR1 | TDP2 4406/4885NSD2 1015/4885HSP90AA1 3101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.