Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.55 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.54 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | FPR2 | P25090 | 1/20 | 0.52 |
| ▸ | ITGAV | P06756 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4097339 | 1.00 | ITGB3 (0.55) | ITGB3ITGA2BITGA4ITGB7MEN1 | |
| SCHEMBL29107666 | 0.86 | ITGA4 (0.56) | ITGB3ITGA2BITGA4ITGB7MEN1 | |
| Trifluoroacetic Acid SCHEMBL3051082 | 0.83 | ITGB3 (0.55) | ITGB3ITGA2BITGAVALDH1A1ALOX15 | |
| SCHEMBL14562475 | 0.82 | ITGA4 (0.56) | ITGB3ITGA2BITGA4ITGB7MEN1 | |
| SCHEMBL14562452 | 0.82 | ITGA4 (0.56) | ITGB3ITGA2BITGA4ITGB7MEN1 | |
| SCHEMBL9825306 | 0.81 | ITGA4 (0.57) | ITGB3ITGA2BITGA4ITGB7MEN1 | |
| SCHEMBL18928696 | 0.81 | ITGA4 (0.56) | ITGB3ITGA2BITGA4ITGB7FPR2 | |
| SCHEMBL8586533 | 0.81 | ITGB3 (0.57) | ITGB3ITGA2BITGAVCTSLCTSB | |
| SCHEMBL4082106 | 0.80 | ALDH1A1 (0.53) | ITGB3ITGA2BITGA4ITGB7MEN1 | |
| SCHEMBL4089152 | 0.80 | ALDH1A1 (0.53) | ITGB3ITGA2BITGA4ITGB7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076285-B2 | Lysobactin amides | AICURIS GMBH & CO. KG (DE) | 2011-12-13 | — | — | US | disclosed |
| US-20090203582-A1 | LYSOBACTIN AMIDES | BAYER HEALTHCARE AG (DE) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203582-A1 | LYSOBACTIN AMIDES | AADAT, HAMP, DLST | ITGB3 2258/4885ITGA2B 1039/4885ITGA4 1185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.