Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4092932 | 0.85 | CYP3A4 (0.52) | CYP3A4CA12CA2CA9ALDH1A1 | |
| SCHEMBL17082322 | 0.82 | CYP3A4 (0.58) | CYP3A4CA12CA2CA9ALDH1A1 | |
| SCHEMBL9909100 | 0.80 | CYP3A4 (0.47) | CYP3A4CA12CA2CA9ALDH1A1 | |
| SCHEMBL18377008 | 0.78 | BACE1 (0.40) | CYP3A4CA12CA2CA9ALDH1A1 | |
| SCHEMBL18037095 | 0.78 | WDR5 (0.47) | LMNATSHRCYP2C9 | |
| SCHEMBL9965355 | 0.78 | LMNA (0.53) | ALDH1A1LMNAPOLBTDP1ACHE | |
| SCHEMBL28437450 | 0.78 | CES2 (0.50) | CYP3A4CA2CA9ALDH1A1LMNA | |
| SCHEMBL3361606 | 0.78 | KMT2A (0.44) | ALDH1A1LMNAHSD17B10TSHRCYP2C9 | |
| SCHEMBL1961835 | 0.78 | ALDH1A1 (0.50) | CYP3A4CA12CA2CA9ALDH1A1 | |
| SCHEMBL30586470 | 0.78 | HPGD (0.42) | ALDH1A1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920083-B2 | Image recording paper medium and image recording method | FUJIFILM CORPORATION (JP) | 2018-03-20 | — | — | US | disclosed |
| US-20160250866-A1 | IMAGE RECORDING PAPER MEDIUM AND IMAGE RECORDING METHOD | FUJIFILM CORPORATION (JP) | 2016-09-01 | — | — | US | disclosed |
| WO-2012015873-A1 | METHOD FOR IMPROVING THE DEPOSIT FORMATION RESISTANCE PERFORMANCE OF TURBINE OILS CONTAINING AMINE ANTIOXIDANTS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2012-02-02 | — | — | WO | disclosed |
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | CANNIZZARO CARINA | 2009-10-01 | — | — | US | disclosed |
| US-20090227543-A1 | PHOSPHONATE COMPOUNDS HAVING IMMUNO-MODULATORY ACTIVITY | CANNIZZARO CARINA | 2009-09-10 | — | — | US | disclosed |
| CN-101410120-A | Anti-inflammatory phosphonate compounds | GILEAD SCIENCES INC (US) | 2009-04-15 | — | — | CN | disclosed |
| US-7470724-B2 | Phosphonate compounds having immuno-modulatory activity | GILEAD SCIENCES, INC. (US) | 2008-12-30 | — | — | US | disclosed |
| US-7432261-B2 | Anti-inflammatory phosphonate compounds | GILEAD SCIENCES, INC. (US) | 2008-10-07 | — | — | US | disclosed |
| US-20060199788-A1 | Anti-inflammatory phosphonate compounds | GILEAD SCIENCES, INC. | 2006-09-07 | — | — | US | disclosed |
| EP-1663254-A2 | ANTI-INFLAMATORY PHOSPHONATE CONJUGATES | GILEAD SCIENCES, INC. (US) | 2006-06-07 | — | — | EP | disclosed |
| US-20060035866-A1 | Phosphonate compounds having immuno-modulatory activity | GILEAD SCIENCES, INC. | 2006-02-16 | — | — | US | disclosed |
| EP-1620110-A2 | IMMUNOMODULATOR PHOSPHONATE CONJUGATES | GILEAD SCIENCES, INC. (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004100960-A2 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2004-11-25 | — | — | WO | disclosed |
| WO-2004096236-A2 | IMMUNOMODULATOR PHOSPHONATE CONJUGATES | GILEAD SCIENCES, INC. (US) | 2004-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060035866-A1 | Phosphonate compounds having immuno-modulatory activity | PHOSPHO1, NFATC1, IFNG | CYP3A4 3919/4885CA12 3364/4885CA2 4123/4885 |
| US-20090227543-A1 | PHOSPHONATE COMPOUNDS HAVING IMMUNO-MODULATORY ACTIVITY | PHOSPHO1, NFATC1, IFNG | CYP3A4 3919/4885CA12 3364/4885CA2 4123/4885 |
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | PHOSPHO1, TNF, PTGES | CYP3A4 1894/4885CA12 2203/4885CA2 732/4885 |
| US-20060199788-A1 | Anti-inflammatory phosphonate compounds | PHOSPHO1, TNF, PTGES | CYP3A4 1894/4885CA12 2203/4885CA2 732/4885 |
| US-20160250866-A1 | IMAGE RECORDING PAPER MEDIUM AND IMAGE RECORDING METHOD | PHOSPHO1, ITPR2, PPIP5K2 | CYP3A4 4706/4885CA12 429/4885CA2 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.