Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4096910 | 0.90 | ALDH1A1 (0.46) | UCHL1NPBWR1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL17458864 | 0.88 | LMNA (0.47) | ALDH1A1L3MBTL1SMN1; SMN2KMT2ARAB9A | |
| SCHEMBL14052805 | 0.88 | GAA (0.55) | ALDH1A1SMN1; SMN2TDP1GAA | |
| SCHEMBL17459012 | 0.85 | CYP11B1 (0.51) | ALDH1A1HPGDSMN1; SMN2MAPTKMT2A | |
| SCHEMBL14801244 | 0.82 | NPBWR1 (0.53) | NPBWR1SMN1; SMN2MAPTDCTPP1NPC1 | |
| SCHEMBL17458955 | 0.82 | DCTPP1 (0.51) | UCHL1NPBWR1SMN1; SMN2MAPTDCTPP1 | |
| SCHEMBL16252258 | 0.82 | UCHL1 (0.56) | UCHL1NPBWR1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL14810739 | 0.82 | UCHL1 (0.53) | UCHL1NPBWR1ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL21518861 | 0.81 | UCHL1 (0.50) | UCHL1NPBWR1ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL5428399 | 0.81 | UCHL1 (0.52) | UCHL1NPBWR1ALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107226807-B | Tankyrase inhibitors | 北京四环制药有限公司 | 2021-01-01 | — | — | CN | disclosed |
| CN-107286169-B | Tankyrase inhibitors | 北京四环制药有限公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-107286169-A | Tankyrase inhibitor | 山东轩竹医药科技有限公司 | 2017-10-24 | — | — | CN | disclosed |
| CN-107226807-A | Tankyrase inhibitor | 山东轩竹医药科技有限公司 | 2017-10-03 | — | — | CN | disclosed |
| US-20090234117-A1 | Pyrazolopyrimidine Derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
| US-20070105890-A1 | Novel condensed imidazole derivative | DAINIPPON SUMITOMO PHARMA CO., LTD | 2007-05-10 | — | — | US | disclosed |
| US-20070105890-A1 | Novel condensed imidazole derivative | DAINIPPON SUMITOMO PHARMA CO., LTD | 2007-05-10 | — | — | US | disclosed |
| US-20070105890-A1 | Novel condensed imidazole derivative | DAINIPPON SUMITOMO PHARMA CO., LTD | 2007-05-10 | — | — | US | disclosed |
| EP-1690863-A1 | NOVEL CONDENSED IMIDAZOLE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105890-A1 | Novel condensed imidazole derivative | DPP4, DPP7, DPP3 | UCHL1 647/4885NPBWR1 1922/4885ALDH1A1 63/4885 |
| US-20090234117-A1 | Pyrazolopyrimidine Derivative | MC2R, CRHR1, AVPR2 | UCHL1 4794/4885NPBWR1 128/4885ALDH1A1 1328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.