SCHEMBL4104428

SCHEMBL4104428

C=CCCCCCCCCOCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.50
TDP1 Q9NUW8 1/20 0.50
TSHR P16473 1/20 0.48
TEAD3 Q99594 2/20 0.46
HRH4 Q9H3N8 1/20 0.42
HRH3 Q9Y5N1 1/20 0.42
GBA1 P04062 2/20 0.41
UGCG Q16739 2/20 0.41
GBA2 Q9HCG7 2/20 0.41
EPHX2 P34913 1/20 0.41
NAAA Q02083 2/20 0.39
KDM4E B2RXH2 1/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
RAB9A P51151 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18936048 1.00 L3MBTL1 (0.50) L3MBTL1TDP1TSHRTEAD3HRH4
SCHEMBL1469764 1.00 L3MBTL1 (0.50) L3MBTL1TDP1TSHRTEAD3HRH4
SCHEMBL2246824 1.00 L3MBTL1 (0.50) L3MBTL1TDP1TSHRTEAD3HRH4
SCHEMBL1164446 1.00 L3MBTL1 (0.50) L3MBTL1TDP1TSHRTEAD3HRH4
SCHEMBL20231370 0.98 TSHR (0.50) L3MBTL1TDP1TSHRTEAD3HRH4
SCHEMBL3269931 0.93 TSHR (0.52) L3MBTL1TDP1TSHRTEAD3HRH4
SCHEMBL24675567 0.90 L3MBTL1 (0.48) L3MBTL1TDP1TSHRTEAD3HRH4
SCHEMBL29026158 0.86 L3MBTL1 (0.40) L3MBTL1TDP1TSHRTEAD3CA1
SCHEMBL101220 0.86 L3MBTL1 (0.53) L3MBTL1TDP1TSHRTEAD3HRH4
SCHEMBL20561263 0.85 L3MBTL1 (0.53) L3MBTL1TDP1TSHRTEAD3HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078082-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2026-03-19 US disclosed
US-20260069549-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2026-03-12 US disclosed
EP-4186888-B1 COMPOUND AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2025-11-26 EP disclosed
US-12404232-B2 Compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2025-09-02 US disclosed
US-20250228777-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2025-07-17 US disclosed
US-12324859-B2 Compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2025-06-10 US disclosed
US-12263248-B2 Compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2025-04-01 US disclosed
US-12151995-B2 Compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2024-11-26 US disclosed
US-20240124388-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2024-04-18 US disclosed
EP-4286012-A2 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ModernaTX, Inc. (US) 2023-12-06 EP disclosed
US-20090197201-A1 FLUOROSURFACTANTS MERCK PATENT GESELLSCHAFT (DE) 2009-08-06 US disclosed
US-20090197201-A1 FLUOROSURFACTANTS MERCK PATENT GESELLSCHAFT (DE) 2009-08-06 US disclosed
EP-2035129-A1 FLUOROSURFACTANTS Merck Patent GmbH (DE) 2009-03-18 EP disclosed
EP-1465876-B1 LONG CHAIN FATTY ALCOHOL SUBSTITUENTS IN ANTINEOPLASTIC AGENTS PFAENDLER HANS RUDOLF (DE) 2008-11-05 EP disclosed
EP-1465876-B1 LONG CHAIN FATTY ALCOHOL SUBSTITUENTS IN ANTINEOPLASTIC AGENTS PFAENDLER HANS RUDOLF (DE) 2008-11-05 EP disclosed
WO-2008003443-A1 FLUOROSURFACTANTS MERCK PATENT GMBH (DE) 2008-01-10 WO disclosed
WO-2008003443-A1 FLUOROSURFACTANTS MERCK PATENT GMBH (DE) 2008-01-10 WO disclosed
US-20040266747-A1 Long chain fatty alcohol substituents in antineoplastic agents PFAENDLER HANS R (DE) 2004-12-30 US disclosed
EP-1465876-A1 LONG CHAIN FATTY ALCOHOL SUBSTITUENTS IN ANTINEOPLASTIC AGENTS Pfaendler, Hans Rudolf (DE) 2004-10-13 EP disclosed
WO-2003055864-A1 LONG CHAIN FATTY ALCOHOL SUBSTITUENTS IN ANTINEOPLASTIC AGENTS PFAENDLER HANS RUDOLF (DE) 2003-07-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12324859-B2 Compounds and compositions for intracellular delivery of therapeutic agents LNPK, PLTP, PLIN3 L3MBTL1 869/4885TDP1 3724/4885TSHR 3089/4885
US-12151995-B2 Compounds and compositions for intracellular delivery of therapeutic agents LNPK, PLTP, PLIN3 L3MBTL1 869/4885TDP1 3724/4885TSHR 3089/4885
US-12263248-B2 Compounds and compositions for intracellular delivery of therapeutic agents LNPK, PLTP, PLIN3 L3MBTL1 869/4885TDP1 3724/4885TSHR 3089/4885
US-20260078082-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS PHOSPHO1, LIPC, SDCBP L3MBTL1 264/4885TDP1 2108/4885TSHR 4134/4885
US-20260069549-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS SIN3A, PLIN3, MSR1 L3MBTL1 632/4885TDP1 4468/4885TSHR 540/4885
US-20040266747-A1 Long chain fatty alcohol substituents in antineoplastic agents FASN, ELOVL3, ELOVL1 L3MBTL1 1168/4885TDP1 1226/4885TSHR 2493/4885
US-12404232-B2 Compounds and compositions for intracellular delivery of therapeutic agents LNPK, PLTP, PLIN3 L3MBTL1 869/4885TDP1 3724/4885TSHR 3089/4885
US-20240124388-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS LNPK, PLTP, PLIN3 L3MBTL1 869/4885TDP1 3724/4885TSHR 3089/4885
US-20090197201-A1 FLUOROSURFACTANTS CBR3, SCO2, FPR3 L3MBTL1 4159/4885TDP1 4231/4885TSHR 1047/4885
US-20250228777-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS LNPK, PLTP, PLIN3 L3MBTL1 869/4885TDP1 3724/4885TSHR 3089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.