Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 3/20 | 0.71 |
| ▸ | NSD2 | O96028 | 1/20 | 0.71 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.71 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.71 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.71 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.62 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | NT5E | P21589 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | DUSP5 | Q16690 | 3/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PKLR | P30613 | 2/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL565059 | 0.88 | PRMT1 (0.71) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL29575770 | 0.88 | PRMT1 (0.71) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL4113771 | 0.87 | NT5E (0.71) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL29702480 | 0.87 | NT5E (0.71) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL10623046 | 0.87 | NT5E (0.71) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| Water SCHEMBL21057100 | 0.86 | PRMT1 (0.69) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| Water SCHEMBL29402350 | 0.86 | PRMT1 (0.69) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| Potassium Ion SCHEMBL18274859 | 0.84 | PRMT1 (0.67) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| Silver SCHEMBL11309326 | 0.84 | NT5E (0.71) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL29399528 | 0.83 | CASP6 (1.00) | CASP6NSD2DUSP3PTPN5PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539803-B | Direct red/direct violet dye compound and preparation method and application thereof | 广东省科学院测试分析研究所(中国广州分析测试中心) | 2024-08-30 | — | — | CN | claimed |
| CN-114539803-A | Direct red/direct violet dye compound and preparation method and application thereof | 广东省科学院测试分析研究所(中国广州分析测试中心) | 2022-05-27 | — | — | CN | claimed |
| CN-102408754-B | Brightening disperse red 3B dye composition and preparation method thereof | UNIV SOOCHOW | 2014-01-08 | — | — | CN | claimed |
| CN-102558900-B | Preparation method for direct blending scarlet D-GLN | WUJIANG MEIYAN SANYOU DYESTUFF CHEMICAL CO LTD | 2013-05-22 | — | — | CN | claimed |
| CN-102558900-A | Preparation method for direct blending scarlet D-GLN | WUJIANG MEIYAN SANYOU DYESTUFF CHEMICAL CO LTD | 2012-07-11 | — | — | CN | claimed |
| CN-102408754-A | Brightening disperse red 3B dye composition and preparation method thereof | UNIV SOOCHOW | 2012-04-11 | — | — | CN | claimed |
| JP-55092696-A | — | — | None | — | — | JP | disclosed |
| CN-114539803-B | Direct red/direct violet dye compound and preparation method and application thereof | 广东省科学院测试分析研究所(中国广州分析测试中心) | 2024-08-30 | — | — | CN | disclosed |
| US-20240084144-A1 | REACTIVE DYES AND PREPARATION METHODS THEREOF | NANTONG UNIVERSITY (CN) | 2024-03-14 | — | — | US | disclosed |
| CN-115386244-B | Double-color-body pH color-changing reactive dye and preparation and application thereof | 南通大学 | 2023-10-20 | — | — | CN | disclosed |
| CN-115368753-B | PH color-changing reactive dye for sweat detection and preparation method thereof | 南通大学 | 2023-08-15 | — | — | CN | disclosed |
| CN-115386244-A | Double-chromophore pH color-changing reactive dye and preparation and application thereof | 南通大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-115368753-A | PH color-changing reactive dye for sweat detection and preparation method thereof | 南通大学 | 2022-11-22 | — | — | CN | disclosed |
| CN-1908077-A | Carbon material | DEGUSSA (DE) | 2007-02-07 | — | — | CN | disclosed |
| US-20060160849-A1 | Pharmaceutical compositions containing sulphonic acid derivatives | ITALFARMACO, S.A. (ES) | 2006-07-20 | — | — | US | disclosed |
| EP-1602644-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING SULPHONIC ACID DERIVATIVES | Italfarmaco, S.A. (ES) | 2005-12-07 | — | — | EP | disclosed |
| US-4230852-A | CELLULOSE, COTTON, ORANGE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-10-28 | — | — | US | disclosed |
| JP-S5592696-A | REAGENT FOR DETECTION OF PEROXIDASE | MITSUI TADAO | 1980-07-14 | — | — | JP | disclosed |
| US-4148790-A | FOR CELLULOSIC FIBERS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1979-04-10 | — | — | US | disclosed |
| US-4038267-A | TRIAZINE REACTIVE DYES | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160849-A1 | Pharmaceutical compositions containing sulphonic acid derivatives | SUCNR1, NR1H4, CYP2B6 | THRB 2260/4885CASP6 2305/4885NSD2 1673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.