Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4131407 | 0.86 | CYP17A1 (0.33) | CYP17A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9854911 | 0.82 | ALOX5 (0.36) | CYP17A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9854842 | 0.81 | TRPM8 (0.41) | CYP17A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14942315 | 0.81 | APP (0.35) | CYP17A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4125025 | 0.81 | CHRNA3 (0.34) | — | |
| SCHEMBL442378 | 0.80 | ALDH1A1 (0.35) | CYP17A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL456036 | 0.80 | CYP2C9 (0.38) | CYP17A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15368074 | 0.79 | RORC (0.37) | CYP17A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4129963 | 0.79 | CHRNB2 (0.40) | — | |
| SCHEMBL26796051 | 0.72 | BRD4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9145403-B2 | Heterocyclic alkanol derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-09-29 | — | — | US | disclosed |
| US-9145403-B2 | Heterocyclic alkanol derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-09-29 | — | — | US | disclosed |
| US-9051308-B2 | — | — | 2015-06-09 | — | — | US | disclosed |
| US-9051308-B2 | — | — | 2015-06-09 | — | — | US | disclosed |
| US-8993776-B2 | Heterocyclic alkanol derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-31 | — | — | US | disclosed |
| US-8993776-B2 | Heterocyclic alkanol derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-31 | — | — | US | disclosed |
| US-8575356-B2 | Heterocyclic alkanol derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-05 | — | — | US | disclosed |
| US-8575356-B2 | Heterocyclic alkanol derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-05 | — | — | US | disclosed |
| US-20130197236-A1 | Novel Heterocyclic Alkanol Derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-08-01 | — | — | US | disclosed |
| US-20130197236-A1 | Novel Heterocyclic Alkanol Derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-08-01 | — | — | US | disclosed |
| US-20130012390-A1 | Novel Heterocyclic Alkanol Derivatives | Beyer Intellectual Property GmbH (DE) | 2013-01-10 | — | — | US | disclosed |
| US-20130012390-A1 | Novel Heterocyclic Alkanol Derivatives | Beyer Intellectual Property GmbH (DE) | 2013-01-10 | — | — | US | disclosed |
| US-20120108423-A1 | Novel Heterocyclic Alkanol Derivatives | BAYER CROPSCIENCE AG (DE) | 2012-05-03 | — | — | US | disclosed |
| US-20120108423-A1 | Novel Heterocyclic Alkanol Derivatives | BAYER CROPSCIENCE AG (DE) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012390-A1 | Novel Heterocyclic Alkanol Derivatives | ERG28, CBR3, MYB | CYP17A1 2729/4885CYP3A4 959/4885CYP2C9 3321/4885 |
| US-20120108423-A1 | Novel Heterocyclic Alkanol Derivatives | ERG28, CBR3, MYB | CYP17A1 2729/4885CYP3A4 959/4885CYP2C9 3321/4885 |
| US-20130197236-A1 | Novel Heterocyclic Alkanol Derivatives | ERG28, CBR3, MYB | CYP17A1 2729/4885CYP3A4 959/4885CYP2C9 3321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.