Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19057264 | 0.95 | CA2 (0.35) | CA2FDPSBLMTDP1 | |
| SCHEMBL15831216 | 0.88 | CA2 (0.30) | CA2 | |
| SCHEMBL10062709 | 0.84 | CA2 (0.47) | CA2FDPSBLMTDP1BTN3A1 | |
| SCHEMBL1758664 | 0.84 | FDPS (0.41) | CA2FDPSBLMTDP1BTN3A1 | |
| SCHEMBL13346159 | 0.82 | CA2 (0.39) | CA2FDPSBLMTDP1BTN3A1 | |
| SCHEMBL13254631 | 0.81 | FDPS (0.39) | CA2FDPSBLMTDP1BTN3A1 | |
| SCHEMBL24469373 | 0.80 | CA2 (0.37) | CA2FDPSBLMTDP1BTN3A1 | |
| SCHEMBL889928 | 0.79 | FDPS (0.53) | CA2FDPSBLMTDP1BTN3A1 | |
| SCHEMBL19387807 | 0.79 | FDPS (0.53) | CA2FDPSBLMTDP1BTN3A1 | |
| Methyl Phosphonate SCHEMBL28129350 | 0.78 | CA2 (0.57) | CA2FDPSBLMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10040814-B2 | Uracyl spirooxetane nucleosides | JANSSEN SCIENCES IRELAND UC (IE) | 2018-08-07 | — | — | US | disclosed |
| US-20180099990-A1 | URACYL SPIROOXETANE NUCLEOSIDES | Janssen Sciences Ireland Unlimited Company (IE) | 2018-04-12 | — | — | US | disclosed |
| US-9845336-B2 | Uracyl spirooxetane nucleosides | JANSSEN SCIENCES IRELAND UC (IE) | 2017-12-19 | — | — | US | disclosed |
| WO-2017176679-A1 | DNA SEQUENCING BY SYNTHESIS WITH NUCLEOTIDE ANALOGUES AND RAMAN DETECTION | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-10-12 | — | — | WO | disclosed |
| US-20170275400-A1 | METHOD FOR PREPARING TERMINAL-MODIFIED CONJUGATED DIENE POLYMER, TERMINAL-MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORPORATION (JP) | 2017-09-28 | — | — | US | disclosed |
| US-20170182181-A1 | PHOSPHATE BASED LINKERS FOR INTRACELLULAR DELIVERY OF DRUG CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2017-06-29 | — | — | US | disclosed |
| US-20170145045-A1 | URACYL SPIROOXETANE NUCLEOSIDES | Janssen Sciences Ireland Unlimited Company (IE) | 2017-05-25 | — | — | US | disclosed |
| US-9657313-B2 | Isoprene oligomer, polyisoprene, processes for producing these materials, rubber composition, and pneumatic tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2017-05-23 | — | — | US | disclosed |
| US-9422323-B2 | Uracyl spirooxetane nucleosides | JANSSEN SCIENCES IRELAND UC (IE) | 2016-08-23 | — | — | US | disclosed |
| US-20160222418-A1 | ISOPRENE OLIGOMER, POLYISOPRENE, PROCESSES FOR PRODUCING THESE MATERIALS, RUBBER COMPOSITION, AND PNEUMATIC TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2016-08-04 | — | — | US | disclosed |
| US-20140171675-A1 | ISOPRENE OLIGOMER, POLYISOPRENE, PROCESSES FOR PRODUCING THESE MATERIALS, RUBBER COMPOSITION, AND PNEUMATIC TIRE | YAMAGATA UNIVERSITY (JP) | 2014-06-19 | — | — | US | disclosed |
| US-20130217648-A1 | Uracyl Spirooxetane Nucleosides | MEDIVIR AB (SE) | 2013-08-22 | — | — | US | disclosed |
| US-8481510-B2 | Uracyl spirooxetane nucleosides | JANSSEN PRODUCTS, LP (US) | 2013-07-09 | — | — | US | disclosed |
| US-8431588-B2 | Cyclopropyl polymerase inhibitors | JANSSEN PRODUCTS, LP (US) | 2013-04-30 | — | — | US | disclosed |
| US-8399429-B2 | Uracyl cyclopropyl nucleotides | JANSSEN PRODUCTS, LP (US) | 2013-03-19 | — | — | US | disclosed |
| US-20120065156-A1 | Uracyl Spirooxetane Nucleosides | TIBOTEC BVBA (BE) | 2012-03-15 | — | — | US | disclosed |
| US-8030096-B2 | Water-soluble rhodamine dyes conjugates | APPLIED BIOSYSTEMS LLC (US) | 2011-10-04 | — | — | US | disclosed |
| US-20110230436-A1 | Uracyl Cyclopropyl Nucleotides | CENTOCOR ORTHO BIOTECH PRODUCTS L.P. (US) | 2011-09-22 | — | — | US | disclosed |
| US-20110092460-A1 | CYCLOPROPYL POLYMERASE INHIBITORS | CENTOCOR ORTHO BIOTECH PRODUCTS L.P. (US) | 2011-04-21 | — | — | US | disclosed |
| US-20110081688-A1 | Water-Soluble Rhodamine Dyes Conjugates | Life Technologies Corporation (US) | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170182181-A1 | PHOSPHATE BASED LINKERS FOR INTRACELLULAR DELIVERY OF DRUG CONJUGATES | CD47, PLPBP, CHERP | CA2 1112/4885FDPS 1631/4885BLM 4171/4885 |
| US-20110092460-A1 | CYCLOPROPYL POLYMERASE INHIBITORS | POLR2E, POLR2H, CTR9 | CA2 2778/4885FDPS 2491/4885BLM 2052/4885 |
| US-10040814-B2 | Uracyl spirooxetane nucleosides | SLC28A1, NUDT1, UMPS | CA2 4491/4885FDPS 1100/4885BLM 2873/4885 |
| US-20140171675-A1 | ISOPRENE OLIGOMER, POLYISOPRENE, PROCESSES FOR PRODUCING THESE MATERIALS, RUBBER COMPOSITION, AND PNEUMATIC TIRE | RCE1, GGPS1, TELO2 | CA2 4386/4885FDPS 47/4885BLM 520/4885 |
| US-20120065156-A1 | Uracyl Spirooxetane Nucleosides | PNP, NUDT1, UMPS | CA2 4764/4885FDPS 1365/4885BLM 1859/4885 |
| US-20170145045-A1 | URACYL SPIROOXETANE NUCLEOSIDES | SLC28A1, NUDT1, UMPS | CA2 4491/4885FDPS 1100/4885BLM 2873/4885 |
| US-20160222418-A1 | ISOPRENE OLIGOMER, POLYISOPRENE, PROCESSES FOR PRODUCING THESE MATERIALS, RUBBER COMPOSITION, AND PNEUMATIC TIRE | RCE1, GGPS1, TELO2 | CA2 4386/4885FDPS 47/4885BLM 520/4885 |
| US-20180099990-A1 | URACYL SPIROOXETANE NUCLEOSIDES | SLC28A1, NUDT1, UMPS | CA2 4401/4885FDPS 1034/4885BLM 3012/4885 |
| US-20130217648-A1 | Uracyl Spirooxetane Nucleosides | PNP, NUDT1, UMPS | CA2 4764/4885FDPS 1365/4885BLM 1859/4885 |
| US-20110230436-A1 | Uracyl Cyclopropyl Nucleotides | NUDT1, PNP, RNGTT | CA2 4567/4885FDPS 1228/4885BLM 2308/4885 |
| US-20110081688-A1 | Water-Soluble Rhodamine Dyes Conjugates | SLC43A3, ABCG2, TARBP1 | CA2 3116/4885FDPS 3392/4885BLM 1548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.