Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | MAX | P61244 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.47 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2294507 | 0.79 | MAPT (0.57) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL1264453 | 0.79 | KMT2A (0.60) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL2080343 | 0.78 | LMNA (0.42) | KMT2AALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL10060154 | 0.78 | PDK2 (0.50) | KMT2AMAPTRAB9ANPC1CRHBP | |
| SCHEMBL668192 | 0.77 | CA12 (0.61) | KMT2AMAPTRAB9ANPC1CRHBP | |
| SCHEMBL30116615 | 0.77 | CYP2C8 (0.55) | MYCMAXLMNA | |
| SCHEMBL2962117 | 0.76 | PPARD (0.51) | KMT2AMAPTCRHBPCRHR2PDK2 | |
| SCHEMBL13247925 | 0.75 | RXRA (0.59) | KMT2AMAPTCRHBPCRHR2PDK2 | |
| SCHEMBL2963618 | 0.75 | ALDH1A1 (0.56) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL5262777 | 0.75 | KMT2A (0.55) | KMT2AALDH1A1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170882-A1 | Methods and compositions | CYTOKINETICS, INCORPORATED | 2009-07-02 | — | — | US | disclosed |
| US-20090170882-A1 | Methods and compositions | CYTOKINETICS, INCORPORATED | 2009-07-02 | — | — | US | disclosed |
| EP-1771176-A2 | METHODS AND COMPOSITIONS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006005063-A2 | METHODS AND COMPOSITIONS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170882-A1 | Methods and compositions | KIF5B, KIF5C, KIF2C | KMT2A 2096/4885ALDH1A1 3367/4885MAPT 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.