SCHEMBL4126701

SCHEMBL4126701

O=Cc1cccc2oc3ccccc3c12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.48
ALDH1A1 P00352 4/20 0.48
KDM4E B2RXH2 3/20 0.48
GLA P06280 2/20 0.48
HPGD P15428 2/20 0.48
HSD17B10 Q99714 2/20 0.48
CYP3A4 P08684 1/20 0.48
MAPT P10636 1/20 0.48
PGAM1 P18669 1/20 0.48
CASP1 P29466 1/20 0.48
CASP7 P55210 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
THRB P10828 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
MEN1 O00255 1/20 0.46
LMNA P02545 1/20 0.46
BLM P54132 1/20 0.46
KMT2A Q03164 1/20 0.46
PTPN1 P18031 2/20 0.46
MAOB P27338 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1942331 0.87 MAOA (0.59) MAOAALDH1A1KDM4EGLAHPGD
SCHEMBL9536657 0.81 MAOA (0.45) MAOAALDH1A1KDM4EGLAHPGD
SCHEMBL5735188 0.80 MAOA (0.44) MAOAALDH1A1KDM4EGLAHPGD
SCHEMBL2158474 0.80 ALDH1A1 (0.43) MAOAALDH1A1KDM4EGLAHPGD
SCHEMBL6006642 0.80 ALDH1A1 (0.43) MAOAALDH1A1KDM4EGLAHPGD
SCHEMBL9450945 0.79 MAOA (0.40) MAOAALDH1A1KDM4EGLAHPGD
SCHEMBL787917 0.78 MAOA (0.44) MAOAALDH1A1KDM4EGLAHPGD
SCHEMBL15427854 0.78 MAOA (0.42) MAOAALDH1A1KDM4EGLAHPGD
SCHEMBL25165121 0.77 ESR1 (0.43) MAOAALDH1A1KDM4EGLAHPGD
SCHEMBL549009 0.76 LMNA (0.57) MAOAALDH1A1KDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113214105-A 150-cavity targeted oseltamivir derivative and preparation method and application thereof 山东大学 2021-08-06 CN claimed
EP-0274574-A2 Composition and method for repelling insects S.C. JOHNSON & SON, INC. (US) 1988-07-20 EP claimed
JP-2248424-A None JP disclosed
US-12091600-B2 Compound and color conversion film comprising same, backlight unit, and display device LG CHEM, LTD. (KR) 2024-09-17 US disclosed
CN-112041322-B9 Compound, color conversion film, backlight unit, and display device including the same 株式会社LG化学 2023-10-17 CN disclosed
CN-112041322-B Compound, color conversion film, backlight unit, and display device including the same 株式会社LG化学 2023-09-08 CN disclosed
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
US-11503831-B2 Arthropoda repellent composition SANDERSTROTHMANN GMBH (DE) 2022-11-22 US disclosed
CN-113214105-B 150-cavity targeted oseltamivir derivative and preparation method and application thereof 山东大学 2022-08-05 CN disclosed
CN-113214105-A 150-cavity targeted oseltamivir derivative and preparation method and application thereof 山东大学 2021-08-06 CN disclosed
US-20210222060-A1 COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD. (KR) 2021-07-22 US disclosed
US-5049581-A Dibenzofurans having anti-tumor activity BURROUGHS WELLCOME CO. (US) 1991-09-17 US disclosed
US-5017600-A Antitumor BURROUGHS WELLCOME CO. (US) 1991-05-21 US disclosed
US-5008286-A Antitumor agents BURROUGHS WELLCOME CO. (US) 1991-04-16 US disclosed
US-4970227-A ANTITUMOR BURROUGHS WELLCOME CO. (US) 1990-11-13 US disclosed
US-4965285-A ANTITUMOR AGENTS BURROUGHS WELLCOME CO. (US) 1990-10-23 US disclosed
JP-H02248424-A AROMATIC POLYMERS IMPERIAL CHEM IND PLC <ICI> 1990-10-04 JP disclosed
US-4866070-A ANTITUMOR AGENT BURROUGHS WELLCOME CO. (US) 1989-09-12 US disclosed
US-4764618-A TRYPSIN INHIBITOR, PANCREATITIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1988-08-16 US disclosed
EP-0183439-A2 Polycyclic compounds, their preparation and use and formulations containing them THE WELLCOME FOUNDATION LIMITED (GB) 1986-06-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS MAOA 934/4885ALDH1A1 2839/4885KDM4E 3740/4885
US-20210222060-A1 COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE CYP1B1, ALDH1A2, ALDH1A1 MAOA 96/4885ALDH1A1 3/4885KDM4E 1692/4885
US-12091600-B2 Compound and color conversion film comprising same, backlight unit, and display device CYP1B1, ALDH1A2, ALDH1A1 MAOA 96/4885ALDH1A1 3/4885KDM4E 1692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.