Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 11/20 | 0.73 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.55 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.49 |
| ▸ | CPT2 | P23786 | 1/20 | 0.48 |
| ▸ | CPT1A | P50416 | 1/20 | 0.48 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26997839 | 0.98 | NOD1 (0.75) | NOD1SLC6A5FAAHMEN1MAPK1 | |
| SCHEMBL851584 | 0.98 | NOD1 (0.75) | NOD1SLC6A5FAAHMEN1MAPK1 | |
| SCHEMBL284836 | 0.98 | NOD1 (0.75) | NOD1SLC6A5FAAHMEN1MAPK1 | |
| SCHEMBL93869 | 0.98 | NOD1 (0.75) | NOD1SLC6A5FAAHMEN1MAPK1 | |
| SCHEMBL322950 | 0.98 | NOD1 (0.75) | NOD1SLC6A5FAAHMEN1MAPK1 | |
| SCHEMBL1899588 | 0.98 | NOD1 (0.75) | NOD1SLC6A5FAAHMEN1MAPK1 | |
| SCHEMBL333310 | 0.98 | NOD1 (0.75) | NOD1SLC6A5FAAHMEN1MAPK1 | |
| SCHEMBL17204500 | 0.98 | NOD1 (0.75) | NOD1SLC6A5FAAHMEN1MAPK1 | |
| SCHEMBL29326 | 0.98 | NOD1 (0.75) | NOD1SLC6A5FAAHMEN1MAPK1 | |
| SCHEMBL19717680 | 0.98 | NOD1 (0.75) | NOD1SLC6A5FAAHMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8323743-B2 | Acrylic-fiber finish, acrylic fiber for carbon-fiber production, and carbon-fiber production method | MATSUMOTO YUSHI-SEIYAKU CO., LTD. (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20120021125-A1 | ACRYLIC-FIBER FINISH, ACRYLIC FIBER FOR CARBON-FIBER PRODUCTION, AND CARBON-FIBER PRODUCTION METHOD | MATSUMOTO YUSHI-SEIYAKU CO., LTD. (JP) | 2012-01-26 | — | — | US | disclosed |