SCHEMBL41497

SCHEMBL41497

COc1ccc(Br)cc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
AOX1 Q06278 1/20 0.52
MAPT P10636 3/20 0.50
CYP1A2 P05177 2/20 0.50
ALOX15 P16050 3/20 0.48
TSHR P16473 2/20 0.48
CYP3A4 P08684 1/20 0.48
NFKB1 P19838 1/20 0.48
ALOX12 P18054 1/20 0.48
APP P05067 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
TP53 P04637 1/20 0.48
MEN1 O00255 2/20 0.47
GAA P10253 2/20 0.47
RECQL P46063 2/20 0.47
KMT2A Q03164 2/20 0.47
HSD17B10 Q99714 2/20 0.47
KDM4E B2RXH2 1/20 0.47
USP2 O75604 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30152196 1.00 ALDH1A1 (0.52) ALDH1A1AOX1MAPTCYP1A2ALOX15
Formaldehyde SCHEMBL27568605 0.94 ALDH1A1 (0.52) ALDH1A1AOX1MAPTCYP1A2ALOX15
Bicarbonate SCHEMBL28501235 0.92 GAA (0.54) ALDH1A1AOX1MAPTCYP1A2MEN1
SCHEMBL2599705 0.89 WDR5 (0.50) ALDH1A1AOX1MAPTALOX15TSHR
SCHEMBL19509694 0.84 ALDH1A1 (0.45) ALDH1A1AOX1MAPTCYP1A2ALOX15
SCHEMBL74689 0.82 MAOB (0.61) ALDH1A1ALOX15TSHRALOX12APP
SCHEMBL29744489 0.82 MAOB (0.61) ALDH1A1ALOX15TSHRALOX12APP
SCHEMBL5606656 0.80 ACHE (0.53) ALDH1A1MAPTCYP1A2ALOX15CYP3A4
SCHEMBL27542420 0.80 MAOB (0.59) ALDH1A1ALOX15TSHRALOX12APP
SCHEMBL30873105 0.79 TUBB4A (0.66) CYP1A2ALOX15TSHRCYP3A4NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 530 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117820101-A Amplified preparation method of Edwan sweet 上海再启生物技术有限公司 2024-04-05 CN claimed
CN-115403456-B Method for synthesizing Edwan sweet intermediate 3-hydroxy-4-methoxy phenylpropionaldehyde 成都大学 2023-11-17 CN claimed
CN-116283978-B Anti-coronavirus compound, and preparation method and application thereof 广州市朝利良生物科技有限公司 2023-08-22 CN claimed
CN-114315528-B Novel method for preparing 4-dimethyl aryl substituted phenol compound by silver catalysis 湖南理工学院 2023-06-27 CN claimed
CN-116283618-A Amine and synthesis method thereof 苏州信礼发医药技术有限公司 2023-06-23 CN claimed
CN-116283978-A Anti-coronavirus compound, and preparation method and application thereof 广州市朝利良生物科技有限公司 2023-06-23 CN claimed
CN-115403456-A Method for synthesizing Edwardsienta intermediate 3-hydroxy-4-methoxyphenylpropanal 成都大学 2022-11-29 CN claimed
CN-114315528-A Novel method for preparing 4-dimethyl aryl substituted phenol compound by silver catalysis 湖南理工学院 2022-04-12 CN claimed
CN-112225647-A Method for synthesizing 5-bromo-2-methoxyphenol 河南中医药大学 2021-01-15 CN claimed
EP-2574192-B1 PROCESS FOR PREPARING AN ORTHO-SUBSTITUTED 5-HALOPHENOL AND A SYNTHESIS INTERMEDIATE THEREOF RHODIA CHINA CO LTD (CN) 2016-09-21 EP claimed
US-8975431-B2 Process for preparing an ortho-substituted 5-halophenol and a synthesis intermediate thereof RHODIA OPERATIONS (FR) 2015-03-10 US claimed
EP-2574192-A1 PROCESS FOR PREPARING AN ORTHO-SUBSTITUTED 5-HALOPHENOL AND A SYNTHESIS INTERMEDIATE THEREOF Rhodia (China) Co., Ltd. (CN) 2013-04-03 EP claimed
US-20130066097-A1 PROCESS FOR PREPARING AN ORTHO-SUBSTITUTED 5-HALOPHENOL AND A SYNTHESIS INTERMEDIATE THEREOF RHODIA (CHINA) CO., LTD. (CN) 2013-03-14 US claimed
WO-2011143819-A1 PROCESS FOR PREPARING AN ORTHO-SUBSTITUTED 5-HALOPHENOL AND A SYNTHESIS INTERMEDIATE THEREOF RHODIA (CHINA) CO., LTD. (CN) 2011-11-24 WO claimed
EP-4748445-A2 BORATE DERIVATIVE AND USES THEREOF Reistone Biopharma Company Limited (CN) 2026-05-27 EP disclosed
US-20260109900-A1 SELF ALIGNMENT AGENT AND LIQUID CRYSTAL COMPOSITION THEREOF JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2026-04-23 US disclosed
CN-121537265-A Preparation method of 1- (2-hydroxy-3-methoxyphenyl) ethanone 常州佳德医药科技有限公司 2026-02-17 CN disclosed
US-3954782-A 2,6-Hydrazino-3-pyridine carboxyamides CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-04 US disclosed
US-3947463-A Certain 2-amino-nicotinonitrile derivatives CASSELLA FARBWERKE MAINKUR AG (DT) 1976-03-30 US disclosed
US-3946024-A INTERMEDIATES FOR AZO DYES CASSELLA FARBWERKE MAINKUR AG (DT) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130066097-A1 PROCESS FOR PREPARING AN ORTHO-SUBSTITUTED 5-HALOPHENOL AND A SYNTHESIS INTERMEDIATE THEREOF HDHD5, HPD, NISCH ALDH1A1 682/4885AOX1 23/4885MAPT 4657/4885
US-20260109900-A1 SELF ALIGNMENT AGENT AND LIQUID CRYSTAL COMPOSITION THEREOF HCN1, HCN2, HCN4 ALDH1A1 4316/4885AOX1 1601/4885MAPT 1860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.