SCHEMBL415427

SCHEMBL415427

CCCCCCCCCCC(C)C(C)(C)P

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.42
SPHK1 Q9NYA1 1/20 0.40
LMNA P02545 1/20 0.39
DNM1 Q05193 2/20 0.39
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
ADH1B P00325 1/20 0.38
ADH1C P00326 1/20 0.38
ADH1A P07327 1/20 0.38
ADH4 P08319 1/20 0.38
ADH7 P40394 1/20 0.38
CA2 P00918 1/20 0.38
ACE2 Q9BYF1 1/20 0.36
GPR84 Q9NQS5 3/20 0.35
FDPS P14324 3/20 0.35
FFAR1 O14842 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL349368 1.00 OPRM1 (0.42) OPRM1SPHK1LMNADNM1TSHR
SCHEMBL2836084 1.00 OPRM1 (0.42) OPRM1SPHK1LMNADNM1TSHR
SCHEMBL8141589 1.00 OPRM1 (0.42) OPRM1SPHK1LMNADNM1TSHR
SCHEMBL2871557 1.00 OPRM1 (0.42) OPRM1SPHK1LMNADNM1TSHR
SCHEMBL1171909 1.00 OPRM1 (0.42) OPRM1SPHK1LMNADNM1TSHR
SCHEMBL413280 1.00 OPRM1 (0.42) OPRM1SPHK1LMNADNM1TSHR
Bromide SCHEMBL5089312 0.98 OPRM1 (0.41) OPRM1SPHK1LMNADNM1TSHR
Iodide SCHEMBL5086753 0.98 OPRM1 (0.41) OPRM1SPHK1LMNADNM1TSHR
Hydrochloric Acid SCHEMBL5085417 0.98 OPRM1 (0.41) OPRM1SPHK1LMNADNM1TSHR
Iodide SCHEMBL5138687 0.98 OPRM1 (0.41) OPRM1SPHK1LMNADNM1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3040421-B1 METHOD FOR MEASURING CHOLESTEROL IN HIGH-DENSITY LIPOPROTEIN, AND REAGENT FOR USE IN SAID METHOD SEKISUI MEDICAL CO LTD (JP) 2018-03-28 EP claimed
US-20160208311-A1 METHOD FOR MEASURING CHOLESTEROL IN HIGH-DENSITY LIPOPROTEIN, AND REAGENT FOR USE IN SAID METHOD SEKISUI MEDICAL CO., LTD. (JP) 2016-07-21 US claimed
EP-3040421-A1 METHOD FOR MEASURING CHOLESTEROL IN HIGH-DENSITY LIPOPROTEIN, AND REAGENT FOR USE IN SAID METHOD Sekisui Medical Co., Ltd. (JP) 2016-07-06 EP claimed
US-8623948-B2 Polycarbonate compositions having antistatic enhancers, method of preparing, and articles comprising the same SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-01-07 US claimed
EP-1832574-B1 Methods of making an antistatic agent SABIC INNOVATIVE PLASTICS IP (NL) 2011-08-10 EP claimed
EP-1737814-B1 METHODS OF MAKING AN ANTISTATIC AGENT SABIC INNOVATIVE PLASTICS IP (NL) 2010-06-09 EP claimed
US-20090326116-A1 POLYCARBONATE COMPOSITIONS HAVING ANTISTATIC ENHANCERS, METHOD OF PREPARING, AND ARTICLES COMPRISING THE SAME SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2009-12-31 US claimed
US-20080269526-A1 METHODS OF MAKING AN ANTISTATIC AGENT SAIC INNOVATIVE PLASTICS, IP B.V. (NL) 2008-10-30 US claimed
JP-2008519077-A 2008-06-05 JP claimed
US-20080015377-A1 METHODS OF MAKING AN ANTISTATIC AGENT GENERAL ELECTRIC COMPANY (US) 2008-01-17 US claimed
WO-2005100307-A2 METHODS OF MAKING AN ANTISTATIC AGENT GENERAL ELECTRIC COMPANY (US) 2005-10-27 WO claimed
US-20050228194-A1 Methods of making an antistatic agent SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2005-10-13 US claimed
US-20050140047-A1 Thermoplastic composition containing polymeric anti-static salt, method of making, and use thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2005-06-30 US claimed
EP-1177256-B1 COMPOSITIONS AND METHODS FOR REDUCED FOOD ADHESION GEN ELECTRIC (US) 2005-06-22 EP claimed
JP-2002543232-A 2002-12-17 JP claimed
JP-2002542358-A 2002-12-10 JP claimed
EP-1177256-A1 COMPOSITIONS AND METHODS FOR REDUCED FOOD ADHESION GENERAL ELECTRIC COMPANY (US) 2002-02-06 EP claimed
EP-1173506-A1 COMPOSITIONS AND METHODS FOR REDUCED FOOD ADHESION GENERAL ELECTRIC COMPANY (US) 2002-01-23 EP claimed
WO-2000064981-A1 COMPOSITIONS AND METHODS FOR REDUCED FOOD ADHESION GENERAL ELECTRIC COMPANY (US) 2000-11-02 WO claimed
WO-2000063283-A1 COMPOSITIONS AND METHODS FOR REDUCED FOOD ADHESION GENERAL ELECTRIC COMPANY (US) 2000-10-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080015377-A1 METHODS OF MAKING AN ANTISTATIC AGENT GPX1, GPX4, PRDX1 OPRM1 274/4885SPHK1 770/4885LMNA 3968/4885
US-20050228194-A1 Methods of making an antistatic agent MTX1, GPX4, CA2 OPRM1 205/4885SPHK1 1138/4885LMNA 3742/4885
US-20080269526-A1 METHODS OF MAKING AN ANTISTATIC AGENT PGM2, CA6, NHERF1 OPRM1 42/4885SPHK1 653/4885LMNA 4473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.