Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | NAAA | Q02083 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MLYCD | O95822 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4180665 | 0.95 | NAAA (0.68) | SMN1; SMN2NAAAL3MBTL1TSHRHTT | |
| SCHEMBL4169513 | 0.93 | NAAA (0.71) | SMN1; SMN2NAAAL3MBTL1MLYCDALDH1A1 | |
| SCHEMBL6716810 | 0.93 | NAAA (0.71) | SMN1; SMN2NAAAL3MBTL1MLYCDALDH1A1 | |
| SCHEMBL9768658 | 0.93 | NAAA (0.71) | SMN1; SMN2NAAAL3MBTL1MLYCDALDH1A1 | |
| SCHEMBL11836345 | 0.93 | NAAA (0.71) | SMN1; SMN2NAAAL3MBTL1MLYCDALDH1A1 | |
| SCHEMBL9771511 | 0.93 | NAAA (0.71) | SMN1; SMN2NAAAL3MBTL1MLYCDALDH1A1 | |
| SCHEMBL11399405 | 0.93 | NAAA (0.71) | SMN1; SMN2NAAAL3MBTL1MLYCDALDH1A1 | |
| SCHEMBL2477903 | 0.89 | KDM4E (0.56) | SMN1; SMN2NAAAL3MBTL1MLYCDALDH1A1 | |
| SCHEMBL28326194 | 0.87 | L3MBTL1 (0.73) | SMN1; SMN2NAAAL3MBTL1TSHRHTT | |
| SCHEMBL6022132 | 0.84 | L3MBTL1 (0.66) | SMN1; SMN2NAAAL3MBTL1MLYCDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247584-A1 | PHENOXY-PIPERIDINES FOR THE TREATMENT OF DISEASES SUCH AS SCHIZOPHRENIA AND DEPRESSION | HOLZEMANN GUNTER | 2009-10-01 | — | — | US | disclosed |
| US-7399569-B2 | Method for producing microcapsules, microcapsules, recording material, and heat-sensitive recording material | FUJIFILM CORPORATION (JP) | 2008-07-15 | — | — | US | disclosed |
| US-20060122191-A1 | N-(indolethyl-)cycloamine compounds | MERCK PATENT GMBH (DE) | 2006-06-08 | — | — | US | disclosed |
| US-7026297-B2 | Neuroprotective agents | UNIVERSITY OF SOUTHAMPTON (GB) | 2006-04-11 | — | — | US | disclosed |
| EP-1572646-A1 | N-(INDOLETHYL-)CACLOAMINE COMPOUNDS | MERCK PATENT GmbH (DE) | 2005-09-14 | — | — | EP | disclosed |
| US-20050187102-A1 | Method for producing microcapsules, microcapsules, recording material, and heat-sensitive recording material | FUJI PHOTO FILM CO., LTD. | 2005-08-25 | — | — | US | disclosed |
| US-20050131021-A1 | Phenoxy piperidines for treating diseases such as schizophrenia and depression | MERCK PATENT GMBH (DE) | 2005-06-16 | — | — | US | disclosed |
| US-20050124554-A1 | Spermidine derivatives for the treatment of chronic neurodegenerative diseases | SOUTHAMPTON, UNIVERSITY OF (GB) | 2005-06-09 | — | — | US | disclosed |
| EP-1471901-A1 | SPERMIDINE DERIVATIVES FOR THE TREATMENT OF CHRONIC NEURODEGENERATIVE DISEASES | UNIVERSITY OF SOUTHAMPTON (GB) | 2004-11-03 | — | — | EP | disclosed |
| EP-1465868-A1 | PHENOXY PIPERIDINES FOR TREATING DISEASES SUCH AS SCHIZOPHRENIA AND DEPRESSION | MERCK PATENT GmbH (DE) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003066037-A1 | SPERMIDINE DERIVATIVES FOR THE TREATMENT OF CHRONIC NEURODEGENERATIVE DISEASES | UNIVERSITY OF SOUTHAMPTON (GB) | 2003-08-14 | — | — | WO | disclosed |
| WO-2003059882-A1 | PHENOXY PIPERIDINES FOR TREATING DISEASES SUCH AS SCHIZOPHRENIA AND DEPRESSION | MERCK PATENT GMBH (DE) | 2003-07-24 | — | — | WO | disclosed |
| EP-1040096-B1 | NEUROPROTECTIVE AGENTS | UNIV SOUTHAMPTON (GB) | 2003-07-09 | — | — | EP | disclosed |
| EP-1040096-A1 | NEUROPROTECTIVE AGENTS | THE UNIVERSITY OF SOUTHAMPTON (GB) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999031049-A1 | NEUROPROTECTIVE AGENTS | UNIVERSITY OF SOUTHAMPTON (GB) | 1999-06-24 | — | — | WO | disclosed |
| US-5496844-A | Indole derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1996-03-05 | — | — | US | disclosed |
| US-5459026-A | N-phosphonoalkylindole derivatives | FUJI PHOTO FILM CO., LTD. (JP) | 1995-10-17 | — | — | US | disclosed |
| EP-0639567-A1 | INDOLE DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1995-02-22 | — | — | EP | disclosed |
| US-H830-H | CONTAINING A DESILVERING ACCELERATOR RELEASING COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1990-10-02 | — | — | US | disclosed |
| US-4198205-A | SULFONIC ACID-FREE DISPERSE DYES | BASF AKTIENGESELLSCHAFT (DE) | 1980-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131021-A1 | Phenoxy piperidines for treating diseases such as schizophrenia and depression | CHRM1, CHRNA3, CHRM2 | SMN1; SMN2 916/4885NAAA 4002/4885L3MBTL1 1140/4885 |
| US-20060122191-A1 | N-(indolethyl-)cycloamine compounds | HTR1A, HTR2A, HTR5A | SMN1; SMN2 233/4885NAAA 2276/4885L3MBTL1 669/4885 |
| US-20050124554-A1 | Spermidine derivatives for the treatment of chronic neurodegenerative diseases | SRM, SMS, PARK7 | SMN1; SMN2 10/4885NAAA 721/4885L3MBTL1 1265/4885 |
| US-20090247584-A1 | PHENOXY-PIPERIDINES FOR THE TREATMENT OF DISEASES SUCH AS SCHIZOPHRENIA AND DEPRESSION | CHRM1, CHRM2, CHRNA5 | SMN1; SMN2 374/4885NAAA 3804/4885L3MBTL1 707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.