Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.43 |
| ▸ | RBP4 | P02753 | 1/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4170621 | 0.86 | MAPT (0.47) | MAPTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL4172479 | 0.84 | ALK (0.50) | MAPTSMN1; SMN2ALDH1A1LMNATP53 | |
| SCHEMBL4174848 | 0.83 | L3MBTL1 (0.61) | MAPTSMN1; SMN2ALDH1A1KMT2AALK | |
| SCHEMBL2205957 | 0.82 | CASP6 (0.59) | MAPTMEN1KMT2ALMNAGFER | |
| SCHEMBL13362096 | 0.82 | HTR1A (0.51) | MAPTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL11294977 | 0.82 | CCR1 (0.46) | MAPTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL1707770 | 0.81 | MAPT (0.57) | MAPTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL4173897 | 0.81 | CCR1 (0.48) | MAPTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL4162968 | 0.80 | LMNA (0.46) | MAPTSMN1; SMN2LMNAUSP2TP53 | |
| SCHEMBL15358736 | 0.80 | ALDH1A1 (0.53) | MAPTMEN1ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061299-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | AVILA THERAPEUTICS, INC. (US) | 2012-05-10 | — | — | WO | disclosed |